Detailed information NTG1006644

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: FX000_RS09710
• Genome accession: NZ_LR698983
• Coordinates: 1883216..1885825 (+)
• Length: 869 a.a.
• NCBI ID: WP_011197985.1
• Uniprot ID: Q65JE2
• Organism: Bacillus licheniformis isolate MGYG-HGUT-02357
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1878216..1890825

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FX000_RS09690	-	1879033..1880208 (+)	1176	WP_009328481.1	glycine C-acetyltransferase	-
FX000_RS09695	miaB	1880352..1881881 (+)	1530	WP_003181965.1	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	-
FX000_RS09700	ymcA	1881883..1882314 (+)	432	WP_003181967.1	RicAFT regulatory complex protein RicA family protein	Regulator
FX000_RS09705	cotE	1882557..1883105 (+)	549	WP_003181968.1	outer spore coat protein CotE	-
FX000_RS09710	hexA	1883216..1885825 (+)	2610	WP_011197985.1	DNA mismatch repair protein MutS	Machinery gene
FX000_RS09715	hexB	1885843..1887753 (+)	1911	WP_003181972.1	DNA mismatch repair endonuclease MutL	Machinery gene
FX000_RS09720	-	1888087..1888368 (+)	282	WP_003181975.1	putative quinol monooxygenase	-
FX000_RS09725	-	1888550..1889077 (+)	528	WP_003181977.1	pre-toxin TG domain-containing protein	-
FX000_RS09730	-	1889074..1889322 (+)	249	WP_080508521.1	HNH/endonuclease VII fold putative polymorphic toxin	-
FX000_RS09735	-	1889378..1889815 (+)	438	WP_011201654.1	hypothetical protein	-

Sequence

Protein

• Length: 869 a.a.
• Molecular weight: 98514.94 Da
• Isoelectric Point: 5.3661

>NTDB_id=1006644 FX000_RS09710 WP_011197985.1 1883216..1885825(+) (hexA) [Bacillus licheniformis isolate MGYG-HGUT-02357]
MAGYTPMIQQYLKIKAEYQDAFLFFRLGDFYEMFFEDAKKASQELEITLTSRDGGSSERIPMCGVPYHSCSSYIEQLIKK
GYKVAICEQVEDPKSAKGVVKREVVQLITPGTVMDGKGIHENENNFIASVSKFQHTYGLAFSDLTTGENLVTAIERLDDV
VSEIYSVGAREIVVSRNLDEKDVAMLKERCGATISFEDEQADEVPGIVNGLGSKELVDTFMRLYVYLKRTQKRSLDHLQN
VQAYELEEAMKIDLYSKRNLELTETIRSKNKKGSLLWLLDETKTAMGGRLLKQWIDRPLIRKGQIEERQEIVETLIAHLF
EREDLRERLKEVYDLERLAGRVAYGNVNARDLIQLKESLKQVPAIKQLVGSLDHPKAKARAEKIDPCGDLLNLLEDALYE
NPPLSLKEGNLIKDGYHAKLDEYRDASKNGKDWIARLEQQEREYTGIRSLKVGFNKVFGYYIEVTKANIHLLEEGRYERK
QTLTNAERYITPELKEKEALILEAENNICELEYELFSELRSKVKEYIPRLQQLAKMMSELDVLQCFATISENRHYVKPEF
SDDVVQVIDGRHPVVEKVMDSQSYVPNSCEMGKGRQMLLITGPNMSGKSTYMRQMALISILAQIGCFVPAKKAVLPIFDQ
IFTRIGAADDLISGQSTFMVEMLEAKNAIVHATKNSLILFDEIGRGTSTYDGMALAQAIIEYVHEHIGAKTLFSTHYHEL
TSLEEKLDDLKNVHVRAEEYEGKVVFLHQIKEGAADKSYGIHVAQLAELPDGLISRAKTILKELESGAKEAAPSTAPNMV
KEAAEEAAATVADQPAQLSFFETDKPIEKETKLSKKEQAVLAEFKAMDLLDMTPIQVMNELYRLQKKLK

Nucleotide

• Length: 2610 bp

>NTDB_id=1006644 FX000_RS09710 WP_011197985.1 1883216..1885825(+) (hexA) [Bacillus licheniformis isolate MGYG-HGUT-02357]
ATGGCAGGCTACACGCCTATGATACAGCAATATTTAAAGATTAAGGCAGAGTATCAGGATGCCTTTTTATTTTTTCGTCT
TGGCGACTTTTATGAGATGTTTTTTGAAGATGCAAAAAAGGCGTCTCAGGAGCTCGAAATCACGCTGACGAGCAGGGACG
GAGGATCAAGCGAAAGAATCCCGATGTGCGGGGTTCCTTATCATTCCTGCTCTTCGTATATCGAACAGCTCATTAAAAAA
GGCTATAAAGTCGCGATCTGTGAACAGGTGGAGGACCCTAAATCGGCCAAAGGAGTCGTCAAAAGGGAAGTCGTGCAGCT
GATCACACCCGGCACCGTGATGGACGGCAAAGGGATTCATGAAAATGAAAACAACTTTATCGCCTCTGTCAGTAAATTTC
AGCATACATACGGGCTCGCTTTTTCTGATTTGACGACGGGCGAGAATTTAGTAACGGCTATCGAAAGGCTTGATGATGTC
GTTTCCGAGATTTACTCTGTCGGAGCAAGGGAAATCGTCGTCAGCCGCAACCTTGACGAGAAAGACGTCGCAATGCTGAA
AGAGCGCTGCGGCGCCACGATCTCTTTCGAGGATGAACAAGCGGATGAAGTGCCTGGCATTGTGAACGGACTGGGGTCCA
AAGAGCTTGTCGATACGTTTATGAGGCTTTACGTCTACTTGAAGCGGACGCAGAAAAGAAGCCTCGACCACCTTCAAAAC
GTTCAGGCCTACGAGCTCGAAGAAGCGATGAAAATCGATTTGTACTCGAAACGCAATCTTGAACTGACGGAAACGATCCG
TTCGAAAAACAAAAAAGGCTCGCTTCTTTGGCTTTTGGATGAAACGAAAACGGCCATGGGAGGGCGGCTGTTAAAGCAAT
GGATCGACAGGCCGCTGATCAGAAAGGGACAGATCGAAGAGCGCCAGGAAATCGTTGAAACGCTGATCGCCCATCTGTTT
GAGCGGGAAGATTTGCGCGAACGGCTGAAGGAAGTATACGACCTCGAGCGGCTCGCCGGAAGGGTCGCATACGGCAACGT
CAACGCCAGAGATTTGATCCAGCTGAAGGAATCGCTGAAACAAGTCCCGGCCATCAAACAGCTTGTCGGCTCCCTCGACC
ATCCGAAAGCAAAAGCGCGCGCCGAGAAAATCGATCCGTGCGGCGATCTTTTGAATCTTTTGGAAGACGCGCTATACGAG
AATCCGCCTCTTTCATTAAAAGAGGGGAACTTAATCAAAGACGGCTACCACGCGAAACTGGATGAATACAGGGACGCAAG
CAAGAACGGAAAAGACTGGATCGCAAGGCTTGAGCAGCAGGAACGCGAGTACACGGGAATCCGCTCTTTAAAAGTCGGCT
TTAACAAGGTGTTCGGCTATTATATTGAAGTGACGAAAGCGAACATCCATCTGCTTGAAGAAGGCCGCTATGAACGGAAG
CAGACGCTGACCAATGCAGAACGCTACATCACGCCGGAGCTGAAAGAAAAAGAAGCCCTGATTCTCGAAGCGGAAAACAA
TATTTGCGAGCTGGAGTATGAGCTGTTTTCCGAGCTTCGCAGCAAGGTGAAGGAATATATCCCGCGCTTGCAGCAGCTGG
CAAAAATGATGAGCGAGCTTGATGTGCTCCAATGTTTTGCGACGATCAGCGAAAACCGGCACTATGTTAAGCCGGAGTTT
TCCGATGATGTCGTTCAGGTGATCGACGGACGGCATCCGGTCGTAGAAAAGGTGATGGACAGCCAGTCTTACGTTCCGAA
CAGCTGTGAAATGGGCAAAGGCAGGCAGATGCTTTTAATCACCGGGCCGAATATGTCCGGGAAAAGCACGTATATGAGAC
AGATGGCGCTGATCTCCATTTTGGCGCAGATCGGCTGCTTTGTTCCTGCGAAAAAAGCGGTGCTGCCGATCTTTGATCAG
ATCTTTACGAGAATTGGCGCAGCGGATGATCTTATATCCGGACAGAGCACGTTTATGGTGGAAATGCTTGAAGCCAAAAA
CGCGATCGTCCATGCGACGAAAAACAGCTTGATTTTATTTGACGAAATCGGCCGGGGTACGTCCACTTACGACGGAATGG
CGCTTGCACAAGCGATCATCGAGTACGTTCACGAGCACATCGGCGCGAAGACTTTATTTTCCACTCACTACCACGAGCTG
ACGTCCCTTGAAGAAAAGCTGGACGATTTGAAGAATGTCCACGTTCGTGCGGAAGAATACGAAGGAAAGGTCGTTTTCCT
TCACCAGATAAAAGAAGGAGCAGCAGATAAAAGCTACGGTATCCATGTCGCGCAGCTGGCTGAATTGCCCGACGGTTTGA
TCAGCAGGGCGAAAACGATCCTGAAAGAACTTGAATCCGGCGCAAAAGAAGCCGCTCCATCAACGGCACCGAATATGGTA
AAAGAGGCGGCGGAAGAAGCCGCGGCGACTGTTGCAGATCAACCGGCCCAGCTGTCATTTTTTGAGACGGACAAGCCAAT
AGAAAAAGAGACGAAGCTCTCCAAAAAAGAGCAGGCTGTTTTAGCCGAATTTAAAGCGATGGATCTGCTCGATATGACGC
CTATACAAGTCATGAATGAACTGTACAGGCTGCAAAAAAAATTAAAGTAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (598-785)

• MutS domain III (MutS_III) (258-547)

• MutS domain I (MutS_I) (5-116)

• MutS domain II (MutS_II) (125-239)

• MutS family domain IV (MutS_IV) (415-506)

3D structure

• AlphaFold DB: Q65JE2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	49.017	99.54	0.488
mutS	Pseudomonas stutzeri strain ATCC 17587	37.528	100	0.381