Detailed information NTG1006486

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ABKP85_RS12320
• Genome accession: NZ_CP157379
• Coordinates: 2404830..2405861 (-)
• Length: 343 a.a.
• NCBI ID: WP_011836077.1
• Uniprot ID: A0A084AC41
• Organism: Lactococcus cremoris strain NZ3900
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2399830..2410861

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABKP85_RS12295 (ABKP85_12260)	-	2399939..2400784 (-)	846	WP_242700777.1	radical SAM protein	-
ABKP85_RS12300 (ABKP85_12265)	-	2400968..2401825 (-)	858	WP_011836073.1	Rgg/GadR/MutR family transcriptional regulator	-
ABKP85_RS12305 (ABKP85_12270)	-	2401877..2403013 (-)	1137	WP_011836074.1	MFS transporter	-
ABKP85_RS12310 (ABKP85_12275)	kwcM	2403010..2404329 (-)	1320	WP_011836075.1	KxxxW cyclic peptide radical SAM maturase	-
ABKP85_RS12315 (ABKP85_12280)	-	2404397..2404510 (-)	114	WP_011836076.1	KxxxW-cyclized peptide pheromone	-
ABKP85_RS12320 (ABKP85_12285)	sepM	2404830..2405861 (-)	1032	WP_011836077.1	SepM family pheromone-processing serine protease	Regulator
ABKP85_RS12325 (ABKP85_12290)	coaD	2405845..2406345 (-)	501	WP_011836078.1	pantetheine-phosphate adenylyltransferase	-
ABKP85_RS12330 (ABKP85_12295)	rsmD	2406393..2406932 (-)	540	WP_011836079.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ABKP85_RS12335 (ABKP85_12300)	-	2407105..2408322 (-)	1218	WP_011836080.1	MFS transporter	-
ABKP85_RS12340 (ABKP85_12305)	lmrP	2408407..2409633 (-)	1227	WP_011836081.1	multidrug efflux MFS transporter LmrP	-
ABKP85_RS12345 (ABKP85_12310)	-	2409868..2410311 (+)	444	WP_041931231.1	sigma-70 family RNA polymerase sigma factor	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37403.02 Da
• Isoelectric Point: 9.9119

>NTDB_id=1006486 ABKP85_RS12320 WP_011836077.1 2404830..2405861(-) (sepM) [Lactococcus cremoris strain NZ3900]
MNKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKISNGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGMMFTLEIYSQLTGKNLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALTYLEK

Nucleotide

• Length: 1032 bp

>NTDB_id=1006486 ABKP85_RS12320 WP_011836077.1 2404830..2405861(-) (sepM) [Lactococcus cremoris strain NZ3900]
ATGAACAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGCCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGGAAAATGGTCAAAGTTGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGTGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGTCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACTGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTACGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGCAGTAAACACAAGTCTACTGGAAAATATATCAAAATCTCTAATGGAAAAACCGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATGATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAAATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAACTTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (229-339)

• PDZ domain (PDZ_2) (135-193)

3D structure

• AlphaFold DB: A0A084AC41

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.406	100	0.487