Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   FJH52_RS05650 Genome accession   NZ_LR595848
Coordinates   1118168..1118632 (+) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain 4559 isolate 4559     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1113168..1123632
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FJH52_RS05620 - 1114170..1114544 (+) 375 WP_001143301.1 phospholipase D-like domain-containing protein -
  FJH52_RS05625 - 1114629..1114832 (+) 204 Protein_1131 transposase -
  FJH52_RS05630 - 1114997..1115935 (+) 939 WP_001828301.1 FRG domain-containing protein -
  FJH52_RS05635 - 1115996..1116709 (+) 714 WP_000499438.1 YjjG family noncanonical pyrimidine nucleotidase -
  FJH52_RS05640 - 1116767..1117369 (+) 603 WP_001810555.1 hypothetical protein -
  FJH52_RS05645 - 1117505..1118158 (+) 654 WP_000401326.1 uracil-DNA glycosylase -
  FJH52_RS05650 mutX 1118168..1118632 (+) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  FJH52_RS05655 - 1118645..1119913 (+) 1269 WP_000924498.1 dihydroorotase -
  FJH52_RS05660 - 1119927..1120187 (+) 261 WP_001105925.1 hypothetical protein -
  FJH52_RS05665 pdrM 1120198..1121559 (+) 1362 WP_000278530.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  FJH52_RS05670 - 1121713..1122681 (+) 969 WP_000105361.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=1006281 FJH52_RS05650 WP_001135768.1 1118168..1118632(+) (mutX) [Streptococcus pneumoniae strain 4559 isolate 4559]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=1006281 FJH52_RS05650 WP_001135768.1 1118168..1118632(+) (mutX) [Streptococcus pneumoniae strain 4559 isolate 4559]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGACGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCTAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987