Detailed information NTG1005739

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXR76_RS09815
• Genome accession: NZ_CP157306
• Coordinates: 1994635..1995678 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN85
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1989635..2000678

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR76_RS09785 (UXR76_009785)	-	1990056..1991312 (-)	1257	WP_336469804.1	aminopeptidase	-
UXR76_RS09790 (UXR76_009790)	-	1991315..1991515 (-)	201	WP_000180460.1	DUF1128 family protein	-
UXR76_RS09795 (UXR76_009795)	-	1991662..1992126 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXR76_RS09800 (UXR76_009800)	-	1992133..1992408 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXR76_RS09805 (UXR76_009805)	-	1992686..1993903 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXR76_RS09810 (UXR76_009810)	vraR	1994016..1994645 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
UXR76_RS09815 (UXR76_009815)	vraS	1994635..1995678 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXR76_RS09820 (UXR76_009820)	liaF	1995675..1996376 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXR76_RS09825 (UXR76_009825)	-	1996391..1996777 (-)	387	Protein_1897	hypothetical protein	-
UXR76_RS09830 (UXR76_009830)	map	1996994..1997752 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXR76_RS09835 (UXR76_009835)	-	1998283..1999269 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
UXR76_RS09840 (UXR76_009840)	-	1999700..2000113 (-)	414	WP_001557448.1	hypothetical protein	-
UXR76_RS09845 (UXR76_009845)	-	2000142..2000252 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1005739 UXR76_RS09815 WP_001017131.1 1994635..1995678(-) (vraS) [Staphylococcus aureus strain BSN85]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1005739 UXR76_RS09815 WP_001017131.1 1994635..1995678(-) (vraS) [Staphylococcus aureus strain BSN85]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1