Detailed information NTG1005695

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ21_RS09695
• Genome accession: NZ_CP157304
• Coordinates: 1968697..1969740 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN65
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1963697..1974740

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ21_RS09665 (UXQ21_09665)	-	1964118..1965374 (-)	1257	WP_001795108.1	aminopeptidase	-
UXQ21_RS09670 (UXQ21_09670)	-	1965377..1965577 (-)	201	WP_000180460.1	DUF1128 family protein	-
UXQ21_RS09675 (UXQ21_09675)	-	1965724..1966188 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ21_RS09680 (UXQ21_09680)	-	1966195..1966470 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ21_RS09685 (UXQ21_09685)	-	1966748..1967965 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXQ21_RS09690 (UXQ21_09690)	vraR	1968078..1968707 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
UXQ21_RS09695 (UXQ21_09695)	vraS	1968697..1969740 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ21_RS09700 (UXQ21_09700)	liaF	1969737..1970438 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ21_RS09705 (UXQ21_09705)	-	1970453..1970839 (-)	387	WP_001110179.1	hypothetical protein	-
UXQ21_RS09710 (UXQ21_09710)	map	1971056..1971814 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXQ21_RS09715 (UXQ21_09715)	-	1972286..1973272 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
UXQ21_RS09720 (UXQ21_09720)	-	1973703..1974116 (-)	414	WP_001557448.1	hypothetical protein	-
UXQ21_RS09725 (UXQ21_09725)	-	1974145..1974255 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1005695 UXQ21_RS09695 WP_001017131.1 1968697..1969740(-) (vraS) [Staphylococcus aureus strain BSN65]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1005695 UXQ21_RS09695 WP_001017131.1 1968697..1969740(-) (vraS) [Staphylococcus aureus strain BSN65]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1