Detailed information NTG1005649

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ86_RS09935
• Genome accession: NZ_CP157303
• Coordinates: 1984040..1985083 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN83
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1979040..1990083

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ86_RS09905 (UXQ86_09905)	-	1979461..1980717 (-)	1257	WP_001795108.1	aminopeptidase	-
UXQ86_RS09910 (UXQ86_09910)	-	1980720..1980920 (-)	201	WP_308869532.1	DUF1128 family protein	-
UXQ86_RS09915 (UXQ86_09915)	-	1981067..1981531 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ86_RS09920 (UXQ86_09920)	-	1981538..1981813 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ86_RS09925 (UXQ86_09925)	-	1982091..1983308 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXQ86_RS09930 (UXQ86_09930)	vraR	1983421..1984050 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
UXQ86_RS09935 (UXQ86_09935)	vraS	1984040..1985083 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ86_RS09940 (UXQ86_09940)	liaF	1985080..1985781 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ86_RS09945 (UXQ86_09945)	-	1985796..1986182 (-)	387	WP_001110179.1	hypothetical protein	-
UXQ86_RS09950 (UXQ86_09950)	map	1986399..1987157 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXQ86_RS09955 (UXQ86_09955)	-	1987688..1988674 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
UXQ86_RS09960 (UXQ86_09960)	-	1989105..1989518 (-)	414	WP_001557448.1	hypothetical protein	-
UXQ86_RS09965 (UXQ86_09965)	-	1989547..1989657 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1005649 UXQ86_RS09935 WP_001017131.1 1984040..1985083(-) (vraS) [Staphylococcus aureus strain BSN83]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1005649 UXQ86_RS09935 WP_001017131.1 1984040..1985083(-) (vraS) [Staphylococcus aureus strain BSN83]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1