Detailed information NTG1005613

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXR77_RS14280
• Genome accession: NZ_CP157302
• Coordinates: 2800332..2801219 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BSN71
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2795332..2806219

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR77_RS14250 (UXR77_014250)	-	2795351..2795443 (+)	93	WP_010956583.1	hypothetical protein	-
UXR77_RS14255 (UXR77_014255)	-	2795551..2796048 (-)	498	WP_001065268.1	glutathione peroxidase	-
UXR77_RS14260 (UXR77_014260)	-	2796058..2796318 (-)	261	WP_001789910.1	hypothetical protein	-
UXR77_RS14265 (UXR77_014265)	-	2796700..2796813 (-)	114	WP_011447078.1	hypothetical protein	-
UXR77_RS14270 (UXR77_014270)	-	2797472..2799472 (-)	2001	WP_337273145.1	ABC transporter permease	-
UXR77_RS14275 (UXR77_014275)	-	2799469..2800224 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXR77_RS14280 (UXR77_014280)	braS	2800332..2801219 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXR77_RS14285 (UXR77_014285)	braR	2801230..2801895 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXR77_RS14290 (UXR77_014290)	-	2801921..2802121 (-)	201	WP_000604728.1	hypothetical protein	-
UXR77_RS14295 (UXR77_014295)	-	2802319..2803743 (+)	1425	WP_000953744.1	alkaline phosphatase	-
UXR77_RS14300 (UXR77_014300)	-	2803803..2803904 (-)	102	WP_000731972.1	SE2200 family small protein	-
UXR77_RS14305 (UXR77_014305)	-	2804026..2804481 (-)	456	Protein_2779	MarR family winged helix-turn-helix transcriptional regulator	-
UXR77_RS14310 (UXR77_014310)	-	2804726..2805487 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1005613 UXR77_RS14280 WP_000143419.1 2800332..2801219(-) (braS) [Staphylococcus aureus strain BSN71]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1005613 UXR77_RS14280 WP_000143419.1 2800332..2801219(-) (braS) [Staphylococcus aureus strain BSN71]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997