Detailed information NTG1005570

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXR68_RS12980
• Genome accession: NZ_CP157301
• Coordinates: 2621426..2622313 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain BSN84
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2616426..2627313

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR68_RS12950 (UXR68_12950)	-	2616435..2616527 (+)	93	WP_031774855.1	hypothetical protein	-
UXR68_RS12955 (UXR68_12955)	-	2616635..2617132 (-)	498	WP_001065267.1	glutathione peroxidase	-
UXR68_RS12960 (UXR68_12960)	-	2617142..2617402 (-)	261	WP_014937088.1	hypothetical protein	-
UXR68_RS12965 (UXR68_12965)	-	2617784..2617897 (-)	114	WP_014937089.1	hypothetical protein	-
UXR68_RS12970 (UXR68_12970)	-	2618566..2620566 (-)	2001	WP_000776741.1	ABC transporter permease	-
UXR68_RS12975 (UXR68_12975)	-	2620563..2621318 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
UXR68_RS12980 (UXR68_12980)	braS	2621426..2622313 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXR68_RS12985 (UXR68_12985)	braR	2622324..2622989 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXR68_RS12990 (UXR68_12990)	-	2623015..2623215 (-)	201	WP_000604731.1	hypothetical protein	-
UXR68_RS12995 (UXR68_12995)	-	2623413..2624837 (+)	1425	WP_000953736.1	alkaline phosphatase	-
UXR68_RS13000 (UXR68_13000)	-	2624897..2624998 (-)	102	WP_000731972.1	SE2200 family small protein	-
UXR68_RS13005 (UXR68_13005)	-	2625120..2625575 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXR68_RS13010 (UXR68_13010)	-	2625819..2626580 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1005570 UXR68_RS12980 WP_000143420.1 2621426..2622313(-) (braS) [Staphylococcus aureus strain BSN84]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1005570 UXR68_RS12980 WP_000143420.1 2621426..2622313(-) (braS) [Staphylococcus aureus strain BSN84]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993