Detailed information NTG1005523

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ90_RS09550
• Genome accession: NZ_CP157300
• Coordinates: 1974125..1975168 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN81
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1969125..1980168

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ90_RS09520 (UXQ90_09520)	-	1969546..1970802 (-)	1257	WP_001793983.1	aminopeptidase	-
UXQ90_RS09525 (UXQ90_09525)	-	1970805..1971005 (-)	201	WP_000180460.1	DUF1128 family protein	-
UXQ90_RS09530 (UXQ90_09530)	-	1971152..1971616 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ90_RS09535 (UXQ90_09535)	-	1971623..1971898 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ90_RS09540 (UXQ90_09540)	-	1972176..1973393 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
UXQ90_RS09545 (UXQ90_09545)	vraR	1973506..1974135 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
UXQ90_RS09550 (UXQ90_09550)	vraS	1974125..1975168 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ90_RS09555 (UXQ90_09555)	liaF	1975165..1975866 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ90_RS09560 (UXQ90_09560)	-	1975881..1976267 (-)	387	WP_001110178.1	hypothetical protein	-
UXQ90_RS09565 (UXQ90_09565)	map	1976484..1977242 (-)	759	WP_000636146.1	type I methionyl aminopeptidase	-
UXQ90_RS09570 (UXQ90_09570)	-	1977942..1978928 (+)	987	WP_001014423.1	aromatic acid exporter family protein	-
UXQ90_RS09575 (UXQ90_09575)	-	1979117..1979530 (-)	414	WP_001643743.1	hypothetical protein	-
UXQ90_RS09580 (UXQ90_09580)	-	1979559..1979669 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1005523 UXQ90_RS09550 WP_001017131.1 1974125..1975168(-) (vraS) [Staphylococcus aureus strain BSN81]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1005523 UXQ90_RS09550 WP_001017131.1 1974125..1975168(-) (vraS) [Staphylococcus aureus strain BSN81]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1