Detailed information NTG1005513

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: FGL16_RS10550
• Genome accession: NZ_LR594043
• Coordinates: 2000484..2003024 (-)
• Length: 846 a.a.
• NCBI ID: WP_024405224.1
• Uniprot ID: -
• Organism: Streptococcus suis strain NCTC10237
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1995484..2008024

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL16_RS10520	-	1996040..1996342 (+)	303	WP_138083579.1	transposase	-
FGL16_RS10525 (NCTC10237_02061)	-	1996704..1997216 (-)	513	WP_014736559.1	transporter accessory protein, putative	-
FGL16_RS10530 (NCTC10237_02062)	-	1997560..1997823 (-)	264	WP_014736561.1	hypothetical protein	-
FGL16_RS10535 (NCTC10237_02063)	-	1997820..1999184 (-)	1365	WP_014736562.1	hypothetical protein	-
FGL16_RS10540 (NCTC10237_02064)	-	1999129..1999857 (-)	729	WP_014736563.1	ABC transporter ATP-binding protein	-
FGL16_RS10545 (NCTC10237_02065)	-	1999914..2000135 (-)	222	WP_014736564.1	hypothetical protein	-
FGL16_RS10550 (NCTC10237_02066)	hexA	2000484..2003024 (-)	2541	WP_024405224.1	DNA mismatch repair protein MutS	Machinery gene
FGL16_RS10555 (NCTC10237_02067)	argR	2003039..2003479 (-)	441	WP_002937036.1	arginine repressor	-
FGL16_RS10560 (NCTC10237_02068)	argS	2003586..2005274 (+)	1689	WP_014736566.1	arginine--tRNA ligase	-
FGL16_RS10570	tnpA	2005416..2005929 (-)	514	Protein_1957	IS200/IS605 family transposase	-
FGL16_RS10575 (NCTC10237_02070)	-	2006257..2007171 (+)	915	WP_014736567.1	SH3 domain-containing protein	-
FGL16_RS10580 (NCTC10237_02071)	-	2007225..2007749 (-)	525	WP_014736568.1	membrane protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95125.63 Da
• Isoelectric Point: 4.8830

>NTDB_id=1005513 FGL16_RS10550 WP_024405224.1 2000484..2003024(-) (hexA) [Streptococcus suis strain NCTC10237]
MATEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAKNPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVAIDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNIPAIKNILQQINEPALGNLVAGLDPIPELHVLISSAIDP
EAQGTITDGNIIRTGFDETLDQYRLVIREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPDHFFRKA
TLKNSERYGTEELAKIEGQMLEARDKSANLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDRGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAELPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLQRADRILQTLENQAPTAPTHPAPSVV
EEPSGQIDLFADTPSHPVLDELEKLDIYNMTPMEVMMAVAELKKKI

Nucleotide

• Length: 2541 bp

>NTDB_id=1005513 FGL16_RS10550 WP_024405224.1 2000484..2003024(-) (hexA) [Streptococcus suis strain NCTC10237]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCACAGTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAGTTATTTTATGAAGATGCGGTAGAAGCGGCACAGATTTTGGAATTGTCCTTGACCAGTC
GGAATAAGAATGCGAAAAATCCGATTCCTATGGCGGGGGTACCGTATCACGCGGCACAACAGTATATCGACACACTTGTT
GAATTGGGGCACAAGGTCGCAATTGCCGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGGGAAGTAGT
GCAGGTCATTACTCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCCGACAGTAACTATTTGGTTGCGATTGACCGTC
AGGGAGTGCAGTTCGCACTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACTAGT
CTTTGCGGTGAAATCCGCAATTTACGGGCACGTGAATTGGTCATCGGCTATGCTTTATCTGAGGAAGAAGAGCAGGTCTT
TTCGAACCAGATGAACCTCCTGCTCTCTTTTGAGGATGAGGTGACGGAAGATGTCCAGCTGATTGACAACTCCTTGACAG
ACTTGGAAAAGGCTGCGGCAGGGAAACTCCTCAGCTACCTACATCGGACTCAGATGCGAGATCTGAGCCACTTGCAAAAG
GTAGTCCACTATGAAATCAAGGACTATCTACAAATGGACTATGCAACCAAGTCCAGCCTGGATCTGCTTGAAAACGGTCG
GACAGGCAAGAAGCATGGTAGTTTGTACTGGTTGTTGGATGAAACCAAGACAGCCATGGGTATGCGACTATTGCGGACAT
GGATTGATCGTCCCTTGATTGATCTTAAGCGGATTGAGAATCGTCAGGCTGTAGTTCAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTCGAGGCTTTAAAAGGTGTCTATGACATCGAACGTTTGGCCAGCCGGGTGTCTTTTGGAAAAAC
CATGCCCAAGGATCTCTTGCAGCTCTCCCAGACTCTGGGAAATATCCCGGCAATCAAGAATATCTTGCAACAAATCAATG
AGCCTGCTCTAGGCAATCTGGTGGCTGGATTGGACCCAATCCCAGAACTGCACGTTCTCATCAGCTCTGCTATTGACCCA
GAAGCCCAAGGGACCATCACAGATGGAAACATCATCCGTACAGGCTTTGACGAAACGCTGGATCAGTATCGTCTGGTCAT
ACGTGAGGGAGCGGGTTGGATTGCGGAGATTGAGGCCAAGGAGCGTGAAGCGTCTGGTATCAATAATCTTAAGATTGATT
ACAATAAAAAAGACGGTTACTATTTCCATGTGACCAATTCCAATCTGGGCAATGTGCCGGACCATTTTTTCCGTAAGGCG
ACCTTGAAAAACTCGGAGCGCTATGGAACGGAAGAGTTGGCTAAGATCGAAGGGCAGATGTTGGAGGCGCGTGATAAGTC
TGCTAATTTGGAGTATGAGATTTTCATGCGGATTCGCCAAGAGGTTGAAAAGTATATCGGTCGCTTGCAGAAGTTGGCTC
GGACTATTGCAACCATCGATGTTTTGCAGGCCTTTGCAGTTGTGGCGGAGCAGCAACATTTGGTTTGTCCACGCTTCACA
GATCAAAGAGAACTGACCATTGACCGTGGTCGTCATGCGGTGGTGGAGAAGGTTATGGGCAAGCAGACCTACATTCCCAA
CTCTATTCACTTGAATACGGATACGCATATGCAACTGATTACAGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGGC
AGTTGGCGGTTATTGTCATCATGGCGCAGATGGGTTCCTATGTGCCTGCGGATCAGGCTGAATTACCGATTTTCGATGCT
ATTTTCACCCGAATTGGGGCGGCAGACGACTTGGTTAGTGGTCAATCGACCTTTATGGTGGAAATGATGGAGGCCAATAA
GGCGGTCCGTCTGGCGACAGATCGGTCGCTCATCCTCTTTGATGAGTTGGGACGGGGAACGGCTACCTATGACGGTATGG
CCCTGGCCCAGTCTATCATCGAGTACATCCACGACAAGATTGGTGCCAAGACCCTCTTTGCCACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACTTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGCCAAGTCACCTTCCT
CCACAAGATTGCCCAAGGTCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCGGGAATGCCAGAGGAACTAC
TGCAGCGGGCGGATAGGATTTTGCAGACACTTGAAAATCAAGCCCCTACTGCACCAACTCACCCAGCTCCGTCAGTAGTG
GAAGAACCGTCTGGTCAAATCGACCTCTTCGCAGACACGCCTTCTCACCCAGTCCTTGATGAACTGGAAAAACTAGACAT
CTACAATATGACCCCTATGGAAGTCATGATGGCAGTGGCGGAGTTGAAGAAAAAAATATAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.995	100	0.74
mutS	Pseudomonas stutzeri strain ATCC 17587	37.762	100	0.383