Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   FGL16_RS09790 Genome accession   NZ_LR594043
Coordinates   1856960..1859413 (-) Length   817 a.a.
NCBI ID   WP_012027858.1    Uniprot ID   A0A0H3N1V1
Organism   Streptococcus suis strain NCTC10237     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1851960..1864413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL16_RS09765 (NCTC10237_01913) hslO 1852203..1853069 (+) 867 WP_002937786.1 Hsp33 family molecular chaperone HslO -
  FGL16_RS09770 (NCTC10237_01914) dusB 1853062..1854066 (+) 1005 WP_002937787.1 tRNA dihydrouridine synthase DusB -
  FGL16_RS09775 (NCTC10237_01915) - 1854212..1854985 (-) 774 WP_012027854.1 NUDIX domain-containing protein -
  FGL16_RS09780 (NCTC10237_01916) pnuC 1854978..1855799 (-) 822 WP_012027855.1 nicotinamide riboside transporter PnuC -
  FGL16_RS09785 (NCTC10237_01917) - 1855809..1856846 (-) 1038 WP_014736445.1 AAA family ATPase -
  FGL16_RS09790 (NCTC10237_01918) clpC 1856960..1859413 (-) 2454 WP_012027858.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  FGL16_RS09795 (NCTC10237_01919) - 1859419..1859877 (-) 459 WP_014736446.1 CtsR family transcriptional regulator -
  FGL16_RS09800 (NCTC10237_01920) - 1860027..1860365 (+) 339 WP_012027860.1 thioredoxin domain-containing protein -
  FGL16_RS09805 (NCTC10237_01921) - 1860365..1861066 (+) 702 WP_012027861.1 hypothetical protein -
  FGL16_RS09810 (NCTC10237_01922) tsf 1861220..1862260 (-) 1041 WP_014736447.1 translation elongation factor Ts -
  FGL16_RS09815 (NCTC10237_01923) rpsB 1862414..1863190 (-) 777 WP_012775356.1 30S ribosomal protein S2 -
  FGL16_RS09820 (NCTC10237_01924) - 1863538..1864050 (-) 513 WP_014736448.1 adenylate kinase -

Sequence

Protein


Download         Length: 817 a.a.        Molecular weight: 90132.53 Da        Isoelectric Point: 6.3138

>NTDB_id=1005507 FGL16_RS09790 WP_012027858.1 1856960..1859413(-) (clpC) [Streptococcus suis strain NCTC10237]
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG

Nucleotide


Download         Length: 2454 bp        

>NTDB_id=1005507 FGL16_RS09790 WP_012027858.1 1856960..1859413(-) (clpC) [Streptococcus suis strain NCTC10237]
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTGGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGGCTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG

Domains

Predicted by InterProScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(14-54)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(104-130)

ATPase family associated with various cellular activities (AAA) (AAA)

(232-364)

AAA domain (Cdc48 subfamily) (AAA_2)

(544-715)

AAA lid domain (AAA_lid_9)

(371-451)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(722-802)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3N1V1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus pneumoniae TIGR4

71.464

99.51

0.711
  clpC Streptococcus pneumoniae Rx1

71.464

99.51

0.711
  clpC Streptococcus pneumoniae D39

71.464

99.51

0.711
  clpC Streptococcus mutans UA159

66.173

99.143

0.656
  clpC Streptococcus thermophilus LMG 18311

64.828

99.878

0.647
  clpC Streptococcus thermophilus LMD-9

64.706

99.878

0.646
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.086

100

0.492
  clpC Bacillus subtilis subsp. subtilis str. 168

44.403

99.51

0.442

Multiple sequence alignment