Detailed information NTG1005463

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ABKA22_RS11600
• Genome accession: NZ_CP157287
• Coordinates: 2295079..2296107 (-)
• Length: 342 a.a.
• NCBI ID: WP_003132657.1
• Uniprot ID: S6FVM6
• Organism: Lactococcus lactis strain BIM B-1834
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2290079..2301107

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABKA22_RS11575 (ABKA22_11575)	-	2290365..2290862 (-)	498	WP_003132662.1	nitroreductase family protein	-
ABKA22_RS11580 (ABKA22_11580)	-	2290849..2291058 (-)	210	WP_003132661.1	hypothetical protein	-
ABKA22_RS11585 (ABKA22_11585)	-	2291055..2291882 (-)	828	WP_058221368.1	radical SAM protein	-
ABKA22_RS11590 (ABKA22_11590)	-	2291875..2293998 (-)	2124	WP_348619058.1	radical SAM protein	-
ABKA22_RS11595 (ABKA22_11595)	-	2294101..2294958 (-)	858	WP_003132658.1	Rgg/GadR/MutR family transcriptional regulator	-
ABKA22_RS11600 (ABKA22_11600)	sepM	2295079..2296107 (-)	1029	WP_003132657.1	SepM family pheromone-processing serine protease	Regulator
ABKA22_RS11605 (ABKA22_11605)	coaD	2296094..2296591 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
ABKA22_RS11610 (ABKA22_11610)	rsmD	2296639..2297178 (-)	540	WP_003132655.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ABKA22_RS11615 (ABKA22_11615)	-	2297349..2298569 (-)	1221	WP_003132654.1	MFS transporter	-
ABKA22_RS11620 (ABKA22_11620)	lmrP	2298653..2299878 (-)	1226	Protein_2257	multidrug efflux MFS transporter LmrP	-
ABKA22_RS11625 (ABKA22_11625)	-	2300066..2300560 (+)	495	WP_012898649.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37349.96 Da
• Isoelectric Point: 9.9183

>NTDB_id=1005463 ABKA22_RS11600 WP_003132657.1 2295079..2296107(-) (sepM) [Lactococcus lactis strain BIM B-1834]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=1005463 ABKA22_RS11600 WP_003132657.1 2295079..2296107(-) (sepM) [Lactococcus lactis strain BIM B-1834]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACAAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGAAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
GACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTGGTGCCTGACTCAGGCACCAAAAAAGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCCGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

3D structure

• AlphaFold DB: S6FVM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491