Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   FGL12_RS09160 Genome accession   NZ_LR594041
Coordinates   1902820..1903737 (-) Length   305 a.a.
NCBI ID   WP_012130833.1    Uniprot ID   A8AZ57
Organism   Streptococcus gordonii strain NCTC9124     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1897820..1908737
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL12_RS09135 (NCTC9124_01840) - 1898152..1898895 (-) 744 WP_041789904.1 DeoR/GlpR family DNA-binding transcription regulator -
  FGL12_RS09140 (NCTC9124_01841) - 1899020..1899796 (+) 777 WP_012130829.1 glycyl-radical enzyme activating protein -
  FGL12_RS09145 (NCTC9124_01842) - 1900103..1900801 (+) 699 WP_012130830.1 ion transporter -
  FGL12_RS09150 (NCTC9124_01843) - 1900876..1901754 (-) 879 WP_012130831.1 ABC transporter permease -
  FGL12_RS09155 (NCTC9124_01844) - 1901747..1902676 (-) 930 WP_012130832.1 ABC transporter ATP-binding protein -
  FGL12_RS09160 (NCTC9124_01845) comR 1902820..1903737 (-) 918 WP_012130833.1 XRE family transcriptional regulator Regulator
  FGL12_RS09165 (NCTC9124_01846) - 1903886..1905778 (-) 1893 WP_012130834.1 M13-type metalloendopeptidase -
  FGL12_RS09170 (NCTC9124_01847) - 1905926..1906645 (+) 720 WP_012130835.1 metal ABC transporter ATP-binding protein -
  FGL12_RS09175 (NCTC9124_01848) - 1906647..1907483 (+) 837 WP_277871562.1 metal ABC transporter permease -
  FGL12_RS09180 (NCTC9124_01849) scaA 1907510..1908442 (+) 933 WP_012130837.1 metal ABC transporter substrate-binding lipoprotein/adhesin ScaA -

Sequence

Protein


Download         Length: 305 a.a.        Molecular weight: 36298.64 Da        Isoelectric Point: 4.5263

>NTDB_id=1005281 FGL12_RS09160 WP_012130833.1 1902820..1903737(-) (comR) [Streptococcus gordonii strain NCTC9124]
MEFKEELGRKIQSLREEKGLSRQAICGVEDILTTRQLQRIEKGQSLPTIATALYIAEQLEVSLDRLANRERFELPSGYLE
LKYRLEKLYHYGDGERLQQREELIEEIYRKYFDQLPEEEQLYLQIKQAKNDMVLTENIAYDQGLIDEYLDQALAKEKLTE
MDLEIIDLRLLALGLKDFDKKEFTCLLNKLLVAVADYPTNGLEKIQTRIIFAAGVLSHYQEYDRLPEILRVLEELMLRRN
DFQDRVFSYALQWKIALFLENNLEKAEDNYQKVKLMLELLPEDVLKENMRLDWEQDIRRYSKIDE

Nucleotide


Download         Length: 918 bp        

>NTDB_id=1005281 FGL12_RS09160 WP_012130833.1 1902820..1903737(-) (comR) [Streptococcus gordonii strain NCTC9124]
GTGGAATTCAAGGAAGAGCTAGGACGGAAGATTCAATCTCTAAGAGAAGAAAAAGGCTTGAGTCGTCAGGCAATTTGTGG
GGTAGAAGACATTTTGACAACGCGGCAACTACAGCGAATTGAAAAAGGCCAGTCTCTGCCTACCATCGCAACAGCTCTCT
ATATTGCTGAGCAACTGGAAGTATCACTAGATAGGCTAGCAAATAGAGAGCGATTCGAATTGCCATCAGGCTATCTTGAA
TTGAAGTATCGCTTGGAAAAGCTATATCACTATGGCGATGGAGAGCGTCTTCAACAGAGAGAAGAGCTGATCGAGGAAAT
CTATCGGAAGTATTTCGATCAGCTCCCTGAGGAAGAACAACTTTATCTTCAGATTAAGCAGGCCAAGAATGATATGGTTT
TAACGGAAAATATTGCCTATGATCAAGGCTTAATAGATGAATATCTGGATCAGGCTTTGGCCAAAGAAAAATTGACGGAA
ATGGATCTAGAAATCATTGATTTACGCCTGTTGGCTCTTGGTTTGAAAGATTTTGATAAGAAGGAGTTTACTTGTTTGCT
AAACAAGTTACTTGTGGCAGTAGCTGATTATCCGACCAATGGATTGGAAAAAATCCAGACCAGAATCATTTTTGCGGCGG
GGGTCTTGTCTCACTATCAAGAATATGACCGACTACCCGAAATATTAAGAGTCCTAGAAGAGCTGATGTTGAGGCGAAAC
GACTTTCAAGATCGTGTCTTTAGCTATGCGCTTCAGTGGAAAATCGCCCTCTTCTTAGAAAACAATCTCGAAAAAGCTGA
GGATAACTATCAAAAGGTCAAGTTAATGCTAGAGCTATTGCCAGAAGATGTCCTTAAGGAGAACATGAGACTGGACTGGG
AGCAGGATATAAGACGCTATAGTAAAATCGATGAATAA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(11-66)

ComR tetratricopeptide (ComR_TPR)

(75-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8AZ57

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

37.71

97.377

0.367