Detailed information NTG1004986

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: FGL00_RS10635
• Genome accession: NZ_LR594034
• Coordinates: 2140459..2143014 (-)
• Length: 851 a.a.
• NCBI ID: WP_046177147.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2135459..2148014

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL00_RS10610 (NCTC8546_02188)	-	2135587..2135940 (-)	354	WP_003058738.1	VOC family protein	-
FGL00_RS10615 (NCTC8546_02189)	-	2135943..2136515 (-)	573	WP_003058799.1	DNA-3-methyladenine glycosylase I	-
FGL00_RS10620 (NCTC8546_02190)	ruvA	2136525..2137118 (-)	594	WP_003058778.1	Holliday junction branch migration protein RuvA	Machinery gene
FGL00_RS10625 (NCTC8546_02191)	-	2137120..2138340 (-)	1221	WP_003058727.1	MFS transporter	-
FGL00_RS10630 (NCTC8546_02192)	hexB	2138351..2140333 (-)	1983	WP_012767642.1	DNA mismatch repair endonuclease MutL	Machinery gene
FGL00_RS10635 (NCTC8546_02193)	hexA	2140459..2143014 (-)	2556	WP_046177147.1	DNA mismatch repair protein MutS	Machinery gene
FGL00_RS10640 (NCTC8546_02194)	-	2143001..2143354 (-)	354	WP_003062220.1	YlbF family regulator	-
FGL00_RS10645 (NCTC8546_02195)	argR	2143351..2143788 (-)	438	WP_138084084.1	arginine repressor	-
FGL00_RS10650 (NCTC8546_02196)	argS	2144077..2145768 (+)	1692	WP_015017500.1	arginine--tRNA ligase	-
FGL00_RS10655 (NCTC8546_02197)	-	2145838..2147235 (-)	1398	WP_014612639.1	ATP-binding cassette domain-containing protein	-

Sequence

Protein

• Length: 851 a.a.
• Molecular weight: 95298.74 Da
• Isoelectric Point: 4.8790

>NTDB_id=1004986 FGL00_RS10635 WP_046177147.1 2140459..2143014(-) (hexA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
MAKANISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLI
ELGYKVAVAEQMEDPKQAVGVVKREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELTAAGKLLQYVHKTQMRELSHLQA
LVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLYWLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFI
ERTDLSNSLKGVYDIERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFNSPFVDKLVNDIDSLPELEYLIRTAIDP
DAPATISEGSIIRNGFDERLDHYRKVMREGTGWIADIEAKERQASGINNLKIDYNKKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERYGTAELAKIEGQMLEAREESSSLEYDIFMCIRAQVETYINRLQKLAKTLATVDVLQSLAAVAETNHYIRPQFN
DNHVIKIQEGRHAVVEKVMGVQEYIPNSISFNQETSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADHVDLPLFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDELGRGTATYDGMALAQAIIEYIHDRVGAKTMFATHYHEL
TDLSTKLTSLVNVHVATLEKDGDVTFLHKIAEGPADKSYGIHVAKIAGLPEALLSRADEVLTRLEAQAQSAEIISVPSKV
EPSSAAREGQLSLFPDEDKSQEIIHTLEAIDVMNMTPLQAMTTLYELKKLL

Nucleotide

• Length: 2556 bp

>NTDB_id=1004986 FGL00_RS10635 WP_046177147.1 2140459..2143014(-) (hexA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
ATGGCAAAAGCTAACATTTCTCCTGGGATGCAACAGTATCTGGACATCAAAAAAGATTATCCAGATGCTTTTTTGCTTTT
CAGGATGGGTGACTTTTATGAATTATTTTATGATGATGCTGTCAAGGCAGCGCAACTTTTAGAGATTGGTTTGACCAGTC
GCAACAAGAATGCGGAAAATCCAATTCCCATGGCAGGAGTGCCACATCATTCTGCCCAGCAATACATTGATGTGTTAATT
GAGTTGGGTTATAAGGTTGCTGTCGCAGAACAAATGGAAGACCCAAAGCAAGCTGTTGGGGTGGTGAAGCGTGAGGTCGT
TCAAGTCATAACTCCTGGAACGGTTGTGGATTCAGCTAAGCCAGATAGCGCCAATAACTTTTTGGTAGCTGTTGACTTTG
ATGGTTGCCGTTATGGATTGGCTTATATGGATGTGTCCACAGGTGAATTTTGCGTGACAGATTTGGCGGACTTTACGAGT
GTTCGTAGCGAAATCCAAAACCTCAAGGCAAAAGAAGTCTTACTAGGTTTTGATTTATCTGAAGAAGAACAGACGATTTT
GGTCAAGCAGATGAATTTGCTGCTTTCTTATGAAGAAACGGTCTATGAAGATAAATCTTTAATTGACGGTCAATTGACAA
CGGTAGAACTGACAGCGGCAGGAAAACTCTTGCAATACGTTCACAAAACACAAATGCGAGAACTCAGCCACTTGCAAGCC
TTGGTTCACTATGAAATCAAGGATTATTTGCAGATGTCGTATGCCACTAAGTCAAGTCTAGATTTGGTAGAGAATGCTAG
AACGAATAAAAAACATGGGAGTCTGTATTGGCTGTTAGATGAAACCAAGACAGCTATGGGGATGAGGCTTTTGCGCTCAT
GGATTGATCGACCTTTGGTTTCTAAAGAAGCTATTTTAGAGCGTCAAGAAATTATTCAAGTTTTTCTGAATGCTTTTATT
GAGCGAACAGATTTAAGCAATAGCTTAAAAGGTGTTTACGATATCGAACGCTTATCTAGCCGTGTGTCTTTTGGCAAGGC
AAATCCGAAAGATTTACTTCAATTGGGGCATACCTTAGCCCAAGTGCCTTATATCAAAGCTATCTTAGAGTCTTTTAATA
GTCCTTTTGTTGACAAACTTGTCAATGATATTGACAGTTTGCCTGAGTTGGAATACTTGATTAGAACAGCCATTGATCCA
GATGCACCAGCAACTATTAGTGAAGGAAGTATTATCCGCAATGGTTTTGATGAGCGCTTGGACCATTATCGTAAAGTAAT
GCGAGAGGGGACAGGCTGGATTGCGGATATTGAGGCCAAAGAGCGTCAAGCAAGTGGCATTAATAACCTAAAAATTGATT
ACAATAAAAAAGATGGTTATTATTTTCACGTTACGAATTCAAATCTTAGCTTAGTTCCCGACCATTTTTTCAGAAAGGCA
ACTTTAAAAAATTCTGAGCGTTATGGAACAGCAGAATTGGCTAAGATTGAAGGTCAGATGTTAGAGGCTAGGGAAGAGTC
ATCTAGTTTAGAATACGATATTTTTATGTGTATTCGAGCTCAAGTTGAAACCTATATTAATCGTTTACAGAAACTGGCTA
AAACTTTGGCAACGGTGGATGTTTTGCAAAGTTTAGCAGCCGTTGCCGAAACCAATCATTATATCCGGCCGCAGTTCAAT
GATAATCATGTGATTAAAATTCAAGAAGGTCGTCACGCGGTTGTTGAAAAGGTTATGGGAGTGCAGGAATACATTCCCAA
TAGTATCTCTTTTAACCAAGAGACAAGCATTCAATTGATTACAGGTCCAAATATGAGCGGTAAGTCGACTTATATGAGAC
AGCTGGCCTTAACGGTTATCATGGCTCAGATGGGCTCATTTGTAGCTGCTGACCATGTTGATTTGCCTCTATTTGATGCG
ATTTTTACGCGTATTGGGGCTGCTGATGATTTGATTTCTGGGCAATCAACCTTTATGGTGGAGATGATGGAAGCAAACCA
AGCAATCAAACGAGCCAGTGACAATTCCCTTATTCTATTTGATGAACTAGGGAGGGGTACGGCAACTTATGATGGTATGG
CACTGGCTCAGGCAATTATCGAATATATCCATGATAGAGTTGGTGCTAAGACCATGTTTGCAACGCACTATCATGAGTTG
ACAGACTTGTCAACTAAGTTGACAAGTCTAGTCAATGTTCATGTAGCAACGCTTGAAAAAGATGGCGATGTAACCTTCCT
TCATAAGATTGCTGAGGGACCGGCGGATAAATCTTACGGTATTCATGTAGCAAAAATAGCAGGACTTCCTGAGGCCCTGC
TAAGCAGAGCAGATGAGGTGCTTACGCGTTTAGAAGCGCAAGCACAATCTGCTGAGATAATATCAGTCCCTTCAAAAGTT
GAGCCAAGCAGCGCTGCTAGAGAGGGACAGTTATCGCTGTTTCCTGATGAGGATAAGTCTCAGGAGATTATTCACACGTT
AGAAGCTATTGATGTGATGAACATGACTCCACTTCAAGCAATGACAACCCTTTACGAATTGAAAAAGTTGTTATAG

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS domain II (MutS_II) (126-239)

• MutS domain V (MutS_V) (599-785)

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-506)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	71.093	100	0.711
mutS	Pseudomonas stutzeri strain ATCC 17587	36.959	100	0.371