Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   FGK91_RS05885 Genome accession   NZ_LR590483
Coordinates   1144360..1145022 (-) Length   220 a.a.
NCBI ID   WP_002995626.1    Uniprot ID   A0A0H2UV22
Organism   Streptococcus pyogenes strain NCTC8318     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1139360..1150022
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK91_RS05865 (NCTC8318_01173) - 1139974..1140156 (-) 183 WP_023078840.1 hypothetical protein -
  FGK91_RS05870 (NCTC8318_01174) sodA 1140323..1140928 (-) 606 WP_023078860.1 superoxide dismutase SodA -
  FGK91_RS05875 (NCTC8318_01175) holA 1141025..1142065 (-) 1041 WP_023078852.1 DNA polymerase III subunit delta -
  FGK91_RS05880 (NCTC8318_01176) comEC/celB 1142136..1144379 (-) 2244 WP_023078854.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  FGK91_RS05885 (NCTC8318_01177) comEA/celA/cilE 1144360..1145022 (-) 663 WP_002995626.1 ComEA family DNA-binding protein Machinery gene
  FGK91_RS05890 (NCTC8318_01178) - 1145222..1145962 (-) 741 WP_021299345.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  FGK91_RS05895 (NCTC8318_01179) - 1146080..1146856 (+) 777 WP_023078849.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  FGK91_RS05900 (NCTC8318_01180) - 1146846..1147124 (+) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  FGK91_RS05905 (NCTC8318_01181) - 1147148..1149148 (-) 2001 WP_030126409.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24623.45 Da        Isoelectric Point: 6.7451

>NTDB_id=1004748 FGK91_RS05885 WP_002995626.1 1144360..1145022(-) (comEA/celA/cilE) [Streptococcus pyogenes strain NCTC8318]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1004748 FGK91_RS05885 WP_002995626.1 1144360..1145022(-) (comEA/celA/cilE) [Streptococcus pyogenes strain NCTC8318]
ATGTTAGACGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGATCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UV22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405

Multiple sequence alignment