Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   E0F34_RS00900 Genome accession   NZ_LR536843
Coordinates   162136..162576 (-) Length   146 a.a.
NCBI ID   WP_000861956.1    Uniprot ID   A0A0H2UNA2
Organism   Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 157136..167576
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F34_RS00870 (SAMEA104035599_00163) - 157397..158683 (+) 1287 WP_000278874.1 response regulator transcription factor -
  E0F34_RS00875 (SAMEA104035599_00164) - 158735..159268 (+) 534 WP_000729030.1 hypothetical protein -
  E0F34_RS00880 (SAMEA104035599_00165) nrdI 159346..159816 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  E0F34_RS00890 (SAMEA104035599_00166) - 160109..161371 (-) 1263 WP_000075807.1 NRAMP family divalent metal transporter -
  E0F34_RS00895 (SAMEA104035599_00167) - 161681..162139 (-) 459 WP_000745059.1 DUF3021 domain-containing protein -
  E0F34_RS00900 (SAMEA104035599_00168) brsR 162136..162576 (-) 441 WP_000861956.1 LytTR family DNA-binding domain-containing protein Regulator
  E0F34_RS00910 (SAMEA104035599_00169) - 163009..163875 (+) 867 WP_000537009.1 helix-turn-helix domain-containing protein -
  E0F34_RS12095 (SAMEA104035599_00170) - 164028..164156 (+) 129 WP_001257108.1 hypothetical protein -
  E0F34_RS00915 (SAMEA104035599_00171) - 164201..164758 (+) 558 WP_000358739.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase -
  E0F34_RS00920 (SAMEA104035599_00173) - 164979..166085 (+) 1107 WP_000608717.1 pyridoxal-dependent decarboxylase -
  E0F34_RS00925 (SAMEA104035599_00174) - 166061..167452 (+) 1392 WP_061714065.1 hypothetical protein -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17183.84 Da        Isoelectric Point: 5.3783

>NTDB_id=1004428 E0F34_RS00900 WP_000861956.1 162136..162576(-) (brsR) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=1004428 E0F34_RS00900 WP_000861956.1 162136..162576(-) (brsR) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UNA2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363