Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   E0F31_RS04920 Genome accession   NZ_LR216064
Coordinates   912985..913449 (+) Length   154 a.a.
NCBI ID   WP_001135782.1    Uniprot ID   P59659
Organism   Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 907985..918449
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F31_RS12185 - 909899..909973 (+) 75 Protein_936 dihydroxyacetone kinase subunit L -
  E0F31_RS04900 dhaM 909973..910353 (+) 381 Protein_937 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  E0F31_RS04905 (SAMEA3714520_00916) - 910812..911525 (+) 714 WP_000499433.1 YjjG family noncanonical pyrimidine nucleotidase -
  E0F31_RS04910 (SAMEA3714520_00917) - 911539..912186 (+) 648 WP_078152000.1 hypothetical protein -
  E0F31_RS04915 (SAMEA3714520_00918) - 912322..912975 (+) 654 WP_000401328.1 uracil-DNA glycosylase -
  E0F31_RS04920 (SAMEA3714520_00919) mutX 912985..913449 (+) 465 WP_001135782.1 NUDIX hydrolase Machinery gene
  E0F31_RS04925 (SAMEA3714520_00920) - 913462..914730 (+) 1269 WP_000924481.1 dihydroorotase -
  E0F31_RS04930 (SAMEA3714520_00921) - 914744..915004 (+) 261 WP_001105925.1 hypothetical protein -
  E0F31_RS04935 (SAMEA3714520_00922) pdrM 915015..916376 (+) 1362 WP_000278533.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  E0F31_RS04940 (SAMEA3714520_00923) - 916530..917498 (+) 969 WP_000105371.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17870.30 Da        Isoelectric Point: 4.2287

>NTDB_id=1003968 E0F31_RS04920 WP_001135782.1 912985..913449(+) (mutX) [Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAVREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGMLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=1003968 E0F31_RS04920 WP_001135782.1 912985..913449(+) (mutX) [Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6]
ATGCCTCAGTTAGCGACGATTTGTTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGTACGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGATGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P59659

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

100

100

1