Detailed information NTG1003774

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ABG197_RS23550
• Genome accession: NZ_CP156996
• Coordinates: 5087033..5088370 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain MPAO1
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5082033..5093370

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABG197_RS23525 (ABG197_23525)	pgeF	5082176..5082904 (-)	729	WP_003112833.1	peptidoglycan editing factor PgeF	-
ABG197_RS23530 (ABG197_23530)	rluD	5082901..5083863 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ABG197_RS23535 (ABG197_23535)	-	5084009..5085034 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ABG197_RS23540 (ABG197_23540)	-	5085191..5085436 (+)	246	WP_003102591.1	PP0621 family protein	-
ABG197_RS23545 (ABG197_23545)	pilS	5085426..5087018 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
ABG197_RS23550 (ABG197_23550)	pilR	5087033..5088370 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ABG197_RS23555 (ABG197_23555)	thiO	5088416..5089510 (-)	1095	WP_010895678.1	glycine oxidase ThiO	-
ABG197_RS23560 (ABG197_23560)	-	5089645..5090154 (+)	510	WP_003112829.1	Tfp pilus assembly protein FimT/FimU	-
ABG197_RS23565 (ABG197_23565)	-	5090260..5090766 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
ABG197_RS23570 (ABG197_23570)	pilV	5090757..5091314 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
ABG197_RS23575 (ABG197_23575)	pilW	5091311..5092135 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
ABG197_RS23580 (ABG197_23580)	pilX	5092132..5092719 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1003774 ABG197_RS23550 WP_003094694.1 5087033..5088370(+) (pilR) [Pseudomonas aeruginosa strain MPAO1]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1003774 ABG197_RS23550 WP_003094694.1 5087033..5088370(+) (pilR) [Pseudomonas aeruginosa strain MPAO1]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384