Detailed information NTG0100370

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: M744_RS10645
• Genome accession: NZ_CP006471
• Coordinates: 2144646..2145803 (-)
• Length: 385 a.a.
• NCBI ID: WP_011242760.1
• Uniprot ID: Q31P88
• Organism: Synechococcus elongatus UTEX 2973
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2139646..2150803

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M744_RS10620 (M744_11135)	-	2140316..2140786 (+)	471	WP_011242755.1	CRR6 family NdhI maturation factor	-
M744_RS10625 (M744_11140)	apbC	2140930..2142015 (+)	1086	WP_011242756.1	iron-sulfur cluster carrier protein ApbC	-
M744_RS10630 (M744_11145)	rodA	2142047..2143312 (+)	1266	WP_011377865.1	rod shape-determining protein RodA	-
M744_RS10635 (M744_11150)	-	2143410..2144141 (+)	732	WP_011377864.1	glucosamine-6-phosphate deaminase	-
M744_RS10640 (M744_11155)	-	2144206..2144634 (-)	429	WP_011242759.1	hypothetical protein	-
M744_RS10645 (M744_11160)	htrA	2144646..2145803 (-)	1158	WP_011242760.1	HhoA/HhoB/HtrA family serine endopeptidase	Regulator
M744_RS10650 (M744_11165)	dnaA	2145913..2147361 (+)	1449	WP_011377863.1	chromosomal replication initiator protein DnaA	-
M744_RS10655 (M744_11170)	ubiE	2147502..2148203 (+)	702	WP_011242762.1	bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE	-
M744_RS10660 (M744_11175)	-	2148206..2149444 (+)	1239	WP_011377862.1	DUF445 family protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 40024.35 Da
• Isoelectric Point: 7.1776

>NTDB_id=100370 M744_RS10645 WP_011242760.1 2144646..2145803(-) (htrA) [Synechococcus elongatus UTEX 2973]
MTDSFFKRTLGLGSLVLLGLGGCSQVAQLPTPPNPLAVNRSEAASPNRPPLPLPENANFIVAAVERDGAAVVRINASRRV
SNGDPFGGLFGGPPAGGNRVERGSGSGFIFDSNGLLMTNAHVVEGADRVQVRLKDGRTYDGQVLGADPVTDVAVVKIDAK
DLPTVRIGNSDNLRPGEWAIAIGNPLGLDNTVTVGIISATGRSSSEVGIPDKRVGFIQTDAAINPGNSGGPLLNAAGEVI
GINTAIRADGQGIGFAVPINTARRIADQIIQTGKASHPLLGVQMLPLTPEIARENNRNPNASIDLPETDGALIVQVLPNS
PAAAAGIRRGDVITAAEGQPIRSASDLQTAVEKKKVGDRLALELLRQQQKRQVTVQLAEIPQQQG

Nucleotide

• Length: 1158 bp

>NTDB_id=100370 M744_RS10645 WP_011242760.1 2144646..2145803(-) (htrA) [Synechococcus elongatus UTEX 2973]
ATGACTGACAGCTTCTTCAAACGAACCTTGGGGCTCGGCAGCCTAGTGCTGCTGGGCTTAGGGGGCTGTTCACAGGTGGC
ACAGTTGCCTACGCCTCCCAATCCACTAGCGGTAAATCGCAGCGAAGCAGCATCACCCAATCGGCCCCCGTTACCCTTGC
CTGAAAACGCCAACTTCATTGTGGCGGCTGTCGAGCGGGATGGCGCTGCCGTGGTTCGGATCAATGCATCCCGCCGTGTC
AGCAATGGCGATCCCTTCGGCGGCTTGTTTGGCGGCCCGCCGGCGGGTGGCAATCGCGTCGAGCGGGGTTCCGGTTCTGG
CTTCATCTTTGATAGTAATGGTCTGCTGATGACCAATGCCCACGTTGTGGAAGGAGCCGATCGCGTTCAAGTGCGGCTCA
AAGACGGCCGAACCTACGATGGCCAAGTCCTAGGTGCTGACCCGGTTACGGATGTGGCCGTCGTCAAAATTGATGCCAAG
GATTTACCGACCGTCCGCATTGGCAATTCCGATAACCTCCGTCCTGGCGAATGGGCAATCGCGATCGGTAATCCCCTCGG
TCTCGACAACACCGTGACGGTGGGCATTATTAGCGCCACTGGGCGTTCGAGTTCAGAAGTTGGGATTCCCGACAAACGGG
TTGGCTTCATTCAGACCGATGCTGCGATCAACCCAGGCAACTCTGGCGGTCCCCTCTTGAATGCTGCTGGCGAAGTGATT
GGCATTAACACCGCGATTCGTGCCGACGGTCAGGGAATTGGCTTCGCGGTACCGATCAACACGGCCCGCCGCATTGCAGA
TCAAATTATTCAGACTGGCAAAGCCTCCCACCCGCTCTTGGGTGTTCAGATGCTGCCGCTGACCCCGGAAATTGCGCGCG
AGAATAACCGTAATCCCAACGCCAGCATTGATCTGCCGGAAACTGACGGTGCCTTAATTGTCCAAGTCTTGCCCAACTCT
CCAGCGGCGGCAGCCGGGATCCGTCGAGGGGACGTGATTACGGCGGCAGAAGGTCAGCCTATCCGCTCAGCTTCGGATCT
CCAGACAGCCGTGGAGAAGAAAAAGGTGGGCGATCGCTTGGCTCTGGAACTGCTCCGTCAGCAACAGAAGCGGCAGGTGA
CGGTTCAGCTGGCTGAAATTCCCCAGCAACAGGGCTAG

Domains

Predicted by InterProScan.

• PDZ domain (PDZ_2) (278-377)

• Peptidase family M50 (Peptidase_M50) (253-380)

• Trypsin-like peptidase domain (Trypsin_2) (105-242)

3D structure

• AlphaFold DB: Q31P88

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	34.889	100	0.369