Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   EL267_RS01505 Genome accession   NZ_LR134520
Coordinates   262488..263822 (+) Length   444 a.a.
NCBI ID   WP_001089364.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NCTC13947     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 257488..268822
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL267_RS01485 (NCTC13947_00295) - 258471..260654 (+) 2184 WP_000795065.1 PTS transporter subunit IIBC -
  EL267_RS01490 (NCTC13947_00296) - 260708..261523 (+) 816 WP_001029866.1 endonuclease/exonuclease/phosphatase family protein -
  EL267_RS01500 (NCTC13947_00297) comE/blpR 261739..262491 (+) 753 WP_001019939.1 response regulator transcription factor Regulator
  EL267_RS01505 (NCTC13947_00298) comD/blpH 262488..263822 (+) 1335 WP_001089364.1 sensor histidine kinase Regulator
  EL267_RS01510 (NCTC13947_00299) - 263911..264075 (-) 165 Protein_262 cysteine peptidase family C39 domain-containing protein -
  EL267_RS01515 - 264364..264537 (+) 174 WP_000683599.1 hypothetical protein -
  EL267_RS01520 (NCTC13947_00300) - 264606..265454 (+) 849 WP_000926582.1 ABC transporter ATP-binding protein -
  EL267_RS01525 (NCTC13947_00301) - 265460..266614 (+) 1155 WP_000623425.1 ABC transporter permease subunit -
  EL267_RS01535 (NCTC13947_00302) - 266843..267877 (+) 1035 WP_000369175.1 acyltransferase family protein -
  EL267_RS01540 (NCTC13947_00303) - 268124..268549 (+) 426 WP_000823117.1 PTS mannose transporter subunit IIA -

Sequence

Protein


Download         Length: 444 a.a.        Molecular weight: 51279.06 Da        Isoelectric Point: 8.0286

>NTDB_id=1003322 EL267_RS01505 WP_001089364.1 262488..263822(+) (comD/blpH) [Streptococcus agalactiae strain NCTC13947]
MNSTLSILEIALTIILTIFLFSKISGRQLTLIEIGICIALRLGLVILFIAANTIINLSFLKYWLLPIYMLSLAFLLLRPI
SKTLVVFYGLFPIVLRNLCSRSLAFFVFPLFNIDFHTTNQGFWGYFVDVLSTLCVLLFLRWMQYDFKALRSSEVSPTDRR
ILQFTNGCMVSYYLLMQFLTYFEYELAINTVIYRQFLLVAYWIIFTGAIASLDRRLRNSLQERLAVQRELQLANMIDYSH
HIEGLYKEVRSFRHDYSNMLTTLKLGIDNEDISIVKSVYQSIFKESNTHFRHPKYNIDRLVNVDNPALKSLLAAKLSQAI
DNHIMVSIEVPDSIKPQGMELIDFITIVSVLWDNAIEASLETDDPKIAMSYFTLKHKQIFIIENSTKEKAIDTSMIFNYE
ISSKGQNRGIGLYNVRGVINRYPNISIATSSQDFSFCQTFEIIL

Nucleotide


Download         Length: 1335 bp        

>NTDB_id=1003322 EL267_RS01505 WP_001089364.1 262488..263822(+) (comD/blpH) [Streptococcus agalactiae strain NCTC13947]
ATGAATTCTACTCTATCCATCTTAGAGATAGCTTTAACGATAATATTAACAATATTTCTCTTTTCTAAAATCAGTGGACG
TCAATTAACTTTAATAGAGATTGGAATTTGTATTGCTCTGAGATTAGGACTTGTAATTTTATTTATAGCAGCTAATACTA
TTATTAATCTTTCATTTCTAAAGTACTGGCTTCTCCCCATCTATATGTTAAGTCTGGCTTTCTTGTTGCTAAGACCTATA
TCTAAAACTTTAGTAGTCTTTTATGGCTTGTTTCCAATTGTTCTCAGAAATCTTTGTTCACGTTCTTTAGCTTTTTTTGT
CTTTCCTTTGTTTAATATTGATTTTCATACAACCAACCAGGGGTTTTGGGGATATTTTGTTGATGTCTTGTCTACTCTTT
GTGTTCTCTTATTTTTAAGATGGATGCAATACGATTTTAAAGCATTGCGAAGTAGTGAAGTTTCGCCAACAGATAGGAGA
ATTCTCCAATTTACGAATGGGTGCATGGTGAGTTATTACTTATTGATGCAGTTTTTAACTTACTTCGAATATGAATTAGC
CATCAATACTGTTATTTACCGACAATTTTTGCTTGTTGCTTATTGGATTATATTTACGGGAGCAATAGCCAGTTTAGACC
GGAGACTTCGAAATTCTTTACAGGAGAGGTTAGCTGTTCAAAGAGAACTCCAATTGGCTAATATGATAGATTATAGCCAC
CATATTGAGGGGTTGTATAAAGAAGTTAGGAGCTTCCGACATGATTATAGTAACATGTTAACGACCTTGAAACTAGGGAT
TGATAATGAAGATATATCTATTGTCAAATCAGTTTATCAGTCTATCTTTAAAGAATCTAATACACATTTCCGACATCCTA
AGTATAATATAGACCGGTTGGTTAATGTAGATAACCCAGCCTTAAAAAGTCTTTTAGCAGCCAAGCTTTCACAAGCGATA
GACAATCATATTATGGTATCTATAGAAGTACCAGACAGTATTAAACCTCAAGGGATGGAACTGATTGATTTTATTACCAT
TGTATCTGTTTTATGGGATAACGCTATTGAGGCTTCTTTAGAGACAGACGATCCTAAGATAGCCATGTCTTATTTTACAT
TAAAACATAAACAAATTTTTATCATAGAAAATTCAACTAAGGAAAAGGCAATAGATACGTCAATGATATTCAATTATGAG
ATAAGTAGTAAGGGACAGAATAGAGGAATAGGTCTTTACAATGTCAGGGGAGTTATCAATCGTTATCCAAATATTTCTAT
TGCAACAAGTAGCCAAGATTTTAGTTTCTGCCAAACTTTCGAAATCATATTATAG

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(339-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

35.683

100

0.365