Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   AACH30_RS02120 Genome accession   NZ_AP027243
Coordinates   435678..437168 (+) Length   496 a.a.
NCBI ID   WP_042217260.1    Uniprot ID   A0A1I4FU19
Organism   Lactococcus garvieae strain L21-68     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 430678..442168
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AACH30_RS02095 (LG21E68_04050) pfkB 430825..431751 (+) 927 WP_265150277.1 1-phosphofructokinase -
  AACH30_RS02100 (LG21E68_04060) - 431766..433670 (+) 1905 WP_014024348.1 fructose-specific PTS transporter subunit EIIC -
  AACH30_RS02105 (LG21E68_04070) - 433782..434024 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  AACH30_RS02110 (LG21E68_04080) - 434241..434792 (+) 552 WP_265150282.1 YceD family protein -
  AACH30_RS02115 (LG21E68_04090) covR 434894..435589 (+) 696 WP_004259096.1 response regulator transcription factor Regulator
  AACH30_RS02120 (LG21E68_04100) covS 435678..437168 (+) 1491 WP_042217260.1 HAMP domain-containing histidine kinase Regulator
  AACH30_RS02125 (LG21E68_04110) - 437565..439136 (+) 1572 WP_265150287.1 ABC transporter permease subunit -
  AACH30_RS02130 (LG21E68_04120) - 439137..439874 (+) 738 WP_265150289.1 amino acid ABC transporter ATP-binding protein -
  AACH30_RS02135 (LG21E68_04130) murD 440013..441374 (+) 1362 WP_265150291.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -

Sequence

Protein


Download         Length: 496 a.a.        Molecular weight: 56767.76 Da        Isoelectric Point: 5.1990

>NTDB_id=100308 AACH30_RS02120 WP_042217260.1 435678..437168(+) (covS) [Lactococcus garvieae strain L21-68]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESTLS
EENLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTNSHGFPLKKDVGDGTHAVRTFGEYSGYLV
ERPVYSNKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLENIDFQDEDLICDPTEVSNFLKKNFLLIHADLSLTVENNLSPGRLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDHGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGEVSVTS
VVGEGSKFTLKIPKIK

Nucleotide


Download         Length: 1491 bp        

>NTDB_id=100308 AACH30_RS02120 WP_042217260.1 435678..437168(+) (covS) [Lactococcus garvieae strain L21-68]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAACAGAAAGTCTTCCCGAGCGTAAGCGAAGCATCATGCTCCGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACCTTCACTATTTTTACAGTATTGGTTTACCAATTGACCATTACAACCTTCA
TCAATTCTGAAAAAGAGGATATGATGAAAGCTCTGGATAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCACATTGTCG
GAAGAAAATCTGGCGAATTATTTGGCTTATGCCAAAGACTATACAGCCTCCAGTCAGGGAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGTTCTAGGAAATCCTTTTATGTTTTTGACGTCGGTGAAAATTTGATTTACTCGACCAATTCTC
ACGGCTTCCCTCTAAAAAAAGATGTGGGGGATGGCACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTC
GAACGACCGGTTTATTCTAATAAAACAGGTAAGCTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTATAG
CGTGCGAACAAAGTTACTGATTGCCCTGATTATCCTAGAGATTATTGCTCTCTTTATCGCTCAGTTTGTCGGTTATTTTA
TGGCGAGTCGTTACATCAAGCCTCTGGAACGGTTGCACGATGCGATTACTACACGTGCCAATAACTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGTGATGAAATTGAAGAACTGGCGACTGTTTATAATGACATGATGATCAAGCTTAACGA
TTATGTTGATCAGCAGAAACGTTTTGTTTCTGATGTCAGTCACGAGTTACGTACGCCACTTGCGGTTTTGGATGGTCATT
TGAATCTCTTGAACCGTTGGGGGAAAAACGATCCTGAGGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTGAGT
ACGATGAGAACAATGTTGGAAGAGATGCTTGCATTGGCCCGTCTTGAAAACATCGATTTTCAAGATGAAGACCTTATCTG
TGATCCAACAGAAGTTTCTAATTTCCTTAAGAAAAACTTCCTACTTATCCATGCTGATTTAAGCTTAACTGTTGAAAATA
ACTTGTCACCGGGAAGATTGGCTCATATCTACCCGAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCTATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATGATAAATACATTATCACTACGGTTGAGGA
TCATGGCTATGGCATTAGTCAGGAAGATTTAAAACATGTCTTTGAGCGTTTCTTCCGTGCTGATAAAGCGCGAAATCGGG
ATATAGGAGGCACTGGGCTTGGACTGTCTATTATCCAACGCATAGTGGAAAACTACGATGGAGAGGTCAGTGTGACTTCT
GTTGTAGGTGAGGGATCGAAATTCACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(214-266)

His Kinase A (phospho-acceptor) domain (HisKA)

(272-337)

ArlS sensor domain (ArlS_N)

(52-190)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(389-494)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I4FU19

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

56.137

100

0.563

Multiple sequence alignment