Detailed information NTG0100301

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: AACH30_RS01740
• Genome accession: NZ_AP027243
• Coordinates: 347949..350399 (+)
• Length: 816 a.a.
• NCBI ID: WP_265150872.1
• Uniprot ID: A0AA43PF33
• Organism: Lactococcus garvieae strain L21-68
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 342949..355399

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AACH30_RS01715 (LG21E68_03290)	-	343856..344368 (+)	513	WP_003134000.1	adenine phosphoribosyltransferase	-
AACH30_RS01720 (LG21E68_03300)	rpoE	344506..345066 (+)	561	WP_003134001.1	DNA-directed RNA polymerase subunit delta	-
AACH30_RS01725 (LG21E68_03310)	mltG	345172..346887 (+)	1716	WP_265150195.1	endolytic transglycosylase MltG	-
AACH30_RS01730 (LG21E68_03320)	greA	346912..347385 (+)	474	WP_265150197.1	transcription elongation factor GreA	-
AACH30_RS01735 (LG21E68_03330)	-	347507..347959 (+)	453	WP_003134006.1	CtsR family transcriptional regulator	-
AACH30_RS01740 (LG21E68_03340)	clpC	347949..350399 (+)	2451	WP_265150872.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
AACH30_RS01745 (LG21E68_03350)	raiA	350523..351080 (+)	558	WP_003134010.1	ribosome-associated translation inhibitor RaiA	-
AACH30_RS01750 (LG21E68_03360)	pflB	351328..353661 (+)	2334	WP_003134012.1	formate C-acetyltransferase	-
AACH30_RS01755 (LG21E68_03370)	coaE	353891..354496 (+)	606	WP_265150200.1	dephospho-CoA kinase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 91105.30 Da
• Isoelectric Point: 6.0528

>NTDB_id=100301 AACH30_RS01740 WP_265150872.1 347949..350399(+) (clpC) [Lactococcus garvieae strain L21-68]
MKFNEKDFTPQVVRVLEKSVDYAHKFNYAWVESSHLLAALAEVPASLAFTLLNSEKIDLEEMLIDIEDFSSQVKTKKSEI
KLSPRVETIIEQARALAQNNDKNRIGTEHLLYMLLANEASFAGQLLREQNINIVNLRKKLEQKAYLRVPERRKAVTPASK
RNLSGKVSETTTTPTLDTVSTDLTKAAREGKLDPMIGREREVERLIHILSRRTKNNPVLVGEPGVGKSAIIEGFATRVAA
GNVPVGLRGSRIMALNMAMVVAGTKFRGEFEDRLTAIVDEVTHDKDVIVFIDELHTIIGAGGGMDSVNDASNILKPALAR
GEFQLIGATTYQEYQKYIEKDEALERRFARVNVEEPSEKETVAILQGLKEKFEAYHAVKFEEGALERAVSLSNRYMPSRR
LPDKAIDLLDEAAAKVKITSKTNYTKLDELKAELKAEELKLQQAVVALDIVEAQGIEKDIERLTHKIDNFTVSENDNPLV
EESDIYAVVSNLTGIPLQQMTKTESERLINLEKELHQRVVGQEEAISAVSRAIRRARSGIADTRRPLGSFMFLGPTGVGK
TELAKALAESVFGSEENMIRVDMSEFMEKFSTSRLIGAPPGYVGYDEGGQLTEQVRNKPYSVILLDEVEKAHPDIFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATAIRDDKTVGFGAKSISTDYAAMKARIMEELKKQYRPEFLNRIDETIVF
HSLTEKEIEQVVKIMSKSLVSRLKDQNITVKFTPAALKVIADKGFDPEYGARPLRKALQREVEDTLSEQLLAGDIHPGDT
ISIGSSNKKIRISVID

Nucleotide

• Length: 2451 bp

>NTDB_id=100301 AACH30_RS01740 WP_265150872.1 347949..350399(+) (clpC) [Lactococcus garvieae strain L21-68]
ATGAAATTTAATGAAAAGGACTTTACACCACAAGTTGTTAGAGTGCTTGAGAAGTCTGTCGACTACGCGCATAAGTTTAA
CTACGCTTGGGTAGAAAGCTCGCACCTATTGGCTGCCTTGGCTGAGGTTCCGGCTTCATTGGCATTTACGCTACTTAATT
CAGAAAAGATTGATTTGGAAGAGATGTTAATCGACATCGAAGATTTTTCAAGTCAAGTGAAGACAAAAAAATCAGAAATA
AAGCTTAGCCCAAGAGTCGAAACGATTATTGAGCAAGCCCGAGCATTGGCTCAAAATAACGATAAAAACCGTATTGGGAC
AGAGCATCTCTTGTATATGCTGTTGGCAAATGAAGCCAGCTTTGCAGGGCAACTTTTACGTGAGCAAAACATTAATATCG
TTAACCTCCGTAAAAAGTTAGAGCAAAAAGCATATTTACGAGTGCCAGAACGCCGTAAAGCGGTGACCCCTGCTTCGAAA
AGAAACCTGTCGGGGAAGGTGTCCGAAACAACAACAACACCTACTTTAGATACAGTCTCGACAGATTTGACAAAAGCAGC
GCGTGAAGGCAAGCTTGATCCAATGATTGGGAGAGAGCGTGAAGTCGAACGTCTTATCCATATTTTGAGTCGCCGTACAA
AGAATAATCCCGTTCTTGTTGGTGAACCAGGAGTTGGTAAGTCAGCCATTATTGAGGGCTTTGCGACACGTGTGGCTGCA
GGAAATGTTCCTGTAGGTTTACGCGGCAGTCGTATCATGGCCTTGAATATGGCGATGGTCGTAGCGGGGACGAAGTTCCG
TGGTGAATTTGAAGATCGTTTGACGGCTATTGTGGATGAAGTGACACATGATAAAGATGTTATCGTCTTTATCGATGAAC
TCCATACTATTATTGGTGCTGGGGGAGGCATGGACTCTGTCAATGATGCCTCAAACATTTTAAAACCCGCATTAGCACGT
GGAGAGTTTCAACTTATTGGTGCTACTACTTATCAAGAATATCAAAAATATATTGAAAAAGATGAAGCTCTGGAGCGCCG
TTTTGCCCGTGTCAATGTCGAAGAACCCTCAGAAAAAGAAACGGTTGCGATTTTACAAGGCTTGAAAGAAAAATTTGAAG
CTTACCATGCAGTCAAATTTGAAGAAGGGGCTTTGGAGCGTGCCGTTAGCTTGAGTAATCGCTACATGCCAAGTCGTCGT
CTGCCAGACAAAGCCATTGATCTTCTTGATGAAGCAGCGGCCAAAGTTAAAATCACGAGTAAAACAAATTACACCAAGCT
AGACGAGTTAAAAGCAGAATTAAAAGCGGAAGAGCTGAAATTACAACAAGCAGTTGTTGCTCTTGATATTGTTGAAGCAC
AAGGAATTGAAAAAGATATTGAAAGATTAACACACAAAATTGATAATTTTACAGTATCGGAAAATGATAATCCTTTGGTC
GAAGAAAGCGATATTTATGCTGTTGTTTCTAACCTTACAGGAATTCCGCTCCAACAAATGACGAAAACAGAAAGTGAACG
TCTGATTAACTTAGAAAAAGAGTTACATCAACGTGTGGTCGGACAGGAAGAAGCGATTTCGGCTGTTTCTCGTGCTATAA
GACGTGCGCGTTCAGGTATTGCTGATACGAGACGTCCTCTGGGCTCATTTATGTTCCTTGGTCCGACAGGGGTGGGGAAA
ACAGAGCTTGCTAAAGCTTTAGCGGAAAGTGTCTTTGGGAGTGAAGAGAACATGATTCGCGTAGACATGAGTGAATTTAT
GGAAAAATTCTCGACATCGCGTCTTATCGGAGCGCCTCCAGGGTATGTAGGTTACGACGAAGGGGGACAATTGACAGAGC
AAGTCCGTAATAAGCCTTATTCTGTTATTCTCCTTGATGAAGTTGAAAAAGCCCATCCTGATATTTTCAATATCATGTTG
CAAATTTTGGATGACGGTTTCGTTACAGATACCAAAGGGCGGAAGGTTGATTTCCGAAATACAATCATCATTATGACATC
CAACTTAGGCGCAACGGCTATTCGTGATGATAAAACGGTTGGTTTTGGAGCTAAATCAATTTCAACAGATTATGCAGCCA
TGAAAGCAAGAATCATGGAAGAACTGAAGAAACAGTACCGTCCAGAATTTCTTAACCGTATCGATGAAACCATCGTTTTC
CATTCACTGACAGAAAAAGAGATTGAACAAGTCGTGAAAATCATGAGTAAATCTCTTGTATCACGTTTGAAAGATCAAAA
TATTACAGTGAAATTTACCCCTGCTGCCTTGAAAGTTATTGCTGATAAAGGATTTGATCCTGAGTATGGTGCACGTCCGT
TGCGTAAAGCGCTACAACGGGAGGTTGAAGACACGCTCAGTGAGCAATTGCTTGCAGGCGACATTCATCCGGGGGATACG
ATTTCGATTGGGTCTTCTAATAAAAAGATTAGAATAAGTGTTATTGATTGA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (357-445)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-349)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (22-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	70.552	99.877	0.705
clpC	Streptococcus thermophilus LMG 18311	49.698	100	0.504
clpC	Streptococcus thermophilus LMD-9	49.698	100	0.504
clpC	Streptococcus pneumoniae TIGR4	49.395	100	0.5
clpC	Streptococcus pneumoniae Rx1	49.274	100	0.499
clpC	Streptococcus pneumoniae D39	49.274	100	0.499
clpC	Streptococcus mutans UA159	47.368	100	0.485
clpC	Bacillus subtilis subsp. subtilis str. 168	48.31	97.917	0.473
clpE	Streptococcus mutans UA159	46.875	78.431	0.368