Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   EL221_RS06360 Genome accession   NZ_LR134496
Coordinates   1215073..1216875 (-) Length   600 a.a.
NCBI ID   WP_002853521.1    Uniprot ID   -
Organism   Campylobacter jejuni strain NCTC13266     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1210073..1221875
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL221_RS06335 (NCTC13266_01262) - 1210202..1211401 (+) 1200 WP_002853994.1 MFS transporter -
  EL221_RS06340 (NCTC13266_01263) ciaC 1211457..1211777 (+) 321 WP_002854052.1 invasion antigen CiaC -
  EL221_RS06345 (NCTC13266_01264) hemE 1211957..1212979 (+) 1023 WP_002853624.1 uroporphyrinogen decarboxylase -
  EL221_RS06350 (NCTC13266_01265) - 1212976..1213878 (+) 903 WP_002853556.1 radical SAM protein -
  EL221_RS06355 (NCTC13266_01266) - 1213875..1215071 (-) 1197 WP_002854153.1 hypothetical protein -
  EL221_RS06360 (NCTC13266_01267) uvrC 1215073..1216875 (-) 1803 WP_002853521.1 excinuclease ABC subunit UvrC Machinery gene
  EL221_RS06365 (NCTC13266_01268) - 1216868..1217362 (-) 495 WP_002868551.1 hypothetical protein -
  EL221_RS06370 (NCTC13266_01269) guaA 1217501..1219036 (+) 1536 WP_002853453.1 glutamine-hydrolyzing GMP synthase -
  EL221_RS06375 (NCTC13266_01270) - 1219123..1220583 (+) 1461 WP_002853652.1 hypothetical protein -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69621.74 Da        Isoelectric Point: 9.4387

>NTDB_id=1002687 EL221_RS06360 WP_002853521.1 1215073..1216875(-) (uvrC) [Campylobacter jejuni strain NCTC13266]
MTKENLENELKTLPNSTGVYQYFNQEGKLLYVGKAKNLKNRVKSYFAFTPNLHANPRNSLRIQKMIEETIHLEFIATNSE
ADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFEEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYPLKQK
ASCKSPCIFYQISRCLAPCDKLISKEKYLEILDEAIHALLNPSVLLKNLEKQMLVLAQNENYEEAAKVRDQIAMIKDLEV
KVEIDIAKLEDFEVFALAFKNSVLSTLRFVVQNGKIISANSKITPIKNDIQWDKNEIYKQLILENFSMDIPLLANVIYVY
EEFEDRVLLEEILSQRFDKKISIKIPKIGEKRRICDLAFQNALLNIEKEQKNHDFTIQKELKFYFELENLPNDIEIFDNS
HLQGVANVGAMVTYRINSWDKSKYRKFHLKHKNDYDQMREVLTRRALDFDKIPPPDLWLIDGGKALLDLAKEIIVSSGAN
VDILAISKEKIDAKAHRAKGGAKDKIHSLKGEFSLSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLNSSKLVNLGLS
SGVIQKLLAYYGNFESIYKADFKDLAMLVGKKAAQKIKEN

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=1002687 EL221_RS06360 WP_002853521.1 1215073..1216875(-) (uvrC) [Campylobacter jejuni strain NCTC13266]
TTGACTAAAGAGAATTTAGAAAATGAGTTAAAAACTCTTCCTAATAGTACTGGCGTTTATCAATACTTCAATCAAGAAGG
AAAGCTTTTATATGTAGGCAAGGCTAAAAATCTTAAAAATCGTGTCAAATCTTATTTTGCCTTTACTCCAAATTTACATG
CAAATCCAAGAAATTCTTTAAGAATTCAAAAAATGATTGAAGAAACAATACATTTGGAATTTATTGCTACTAATTCAGAG
GCTGATGCTTTGATTTTAGAAAATTCTTTTATCAAACAACTGCATCCAAAATATAATATTTTGCTAAGAGATGATAAAAC
TTATCCTTATATTTATGTGGATTTTGAAGAAGAATTTCCACGCTTTGAGATCACTAGAAAATTAGTAAAAAAAAGCAAAA
TTAAATATTTTGGCCCTTTTTTTAAAGGCGCTAGAGAGCTTTTAGATGCGCTTTATTTATACTATCCTTTAAAGCAAAAA
GCAAGTTGTAAATCCCCTTGTATTTTTTATCAAATTTCTCGTTGTCTTGCGCCTTGTGATAAACTCATCAGCAAAGAAAA
ATACCTTGAAATTTTAGATGAGGCTATACACGCACTTTTAAATCCTAGTGTTTTGCTTAAAAACTTAGAAAAACAAATGC
TTGTTTTAGCACAAAATGAAAATTACGAAGAAGCAGCTAAAGTAAGAGATCAGATTGCAATGATTAAAGATTTGGAAGTT
AAGGTTGAAATAGATATTGCAAAATTAGAAGATTTTGAAGTATTTGCTTTAGCTTTTAAAAATTCCGTGCTTTCAACCTT
GCGTTTTGTGGTGCAAAATGGAAAAATTATCAGTGCAAATTCTAAGATTACTCCTATAAAAAATGATATACAATGGGATA
AAAATGAAATTTATAAGCAACTGATTTTAGAAAATTTTAGCATGGATATTCCTTTGCTTGCAAATGTTATTTATGTTTAT
GAAGAATTTGAAGATAGAGTGCTTTTAGAAGAAATTTTAAGCCAAAGGTTTGATAAAAAAATCAGTATTAAAATCCCTAA
AATAGGAGAAAAAAGAAGAATTTGTGATTTGGCTTTTCAAAATGCCCTTTTAAATATAGAAAAAGAGCAAAAAAATCATG
ATTTTACTATACAAAAAGAATTAAAGTTTTATTTTGAGCTTGAAAATTTACCAAATGATATAGAAATTTTTGACAATTCT
CATTTGCAAGGCGTGGCAAATGTTGGAGCTATGGTAACTTATAGAATAAATTCTTGGGATAAGTCAAAATATAGAAAATT
TCATTTAAAACATAAAAATGACTATGATCAAATGCGTGAAGTTTTAACGCGTAGGGCTTTGGACTTTGATAAAATACCTC
CTCCTGATTTATGGCTTATAGACGGGGGAAAGGCTTTGCTTGATTTGGCTAAAGAAATCATTGTAAGTAGTGGGGCAAAT
GTCGATATTTTAGCTATTTCAAAAGAAAAAATCGATGCAAAAGCACATAGAGCTAAAGGGGGTGCTAAGGATAAAATTCA
TTCCTTAAAAGGAGAATTTAGTCTAAGCATTAACGATAAAAAACTACAATTCTTACAGAAATTAAGAGATGAAGCACACC
GTTTTGCTATCAGCTTTCATCAAAATACTAAGAAAAAACAGGACTTGAATAGTTCTAAGCTTGTAAATTTAGGACTTAGT
TCAGGGGTTATACAAAAACTTTTAGCGTATTATGGAAATTTTGAATCTATATATAAGGCTGATTTTAAAGATCTTGCAAT
GCTTGTAGGCAAGAAAGCGGCGCAAAAGATAAAGGAAAATTGA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-537)

UvrB/uvrC motif (UVR)

(205-237)

GIY-YIG catalytic domain (GIY-YIG)

(18-99)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

47.251

97

0.458

Multiple sequence alignment