Detailed information NTG0100256

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: AACH63_RS01895
• Genome accession: NZ_AP027240
• Coordinates: 369455..371905 (+)
• Length: 816 a.a.
• NCBI ID: WP_185767512.1
• Uniprot ID: -
• Organism: Lactococcus formosensis strain L21-20
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 364455..376905

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AACH63_RS01870 (LG21E20_03600)	mltG	364567..366279 (+)	1713	WP_096368661.1	endolytic transglycosylase MltG	-
AACH63_RS01875 (LG21E20_03610)	greA	366305..366778 (+)	474	WP_017369377.1	transcription elongation factor GreA	-
AACH63_RS01880	-	366964..367152 (+)	189	WP_338720992.1	hypothetical protein	-
AACH63_RS01885	-	367239..368890 (+)	1652	Protein_362	hypothetical protein	-
AACH63_RS01890 (LG21E20_03650)	-	369013..369465 (+)	453	WP_096368658.1	CtsR family transcriptional regulator	-
AACH63_RS01895 (LG21E20_03660)	clpC	369455..371905 (+)	2451	WP_185767512.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
AACH63_RS01900 (LG21E20_03670)	raiA	372028..372585 (+)	558	WP_003134010.1	ribosome-associated translation inhibitor RaiA	-
AACH63_RS01905 (LG21E20_03680)	pflB	372833..375166 (+)	2334	WP_019292664.1	formate C-acetyltransferase	-
AACH63_RS01910 (LG21E20_03690)	coaE	375627..376232 (+)	606	WP_096368656.1	dephospho-CoA kinase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 91106.33 Da
• Isoelectric Point: 6.0545

>NTDB_id=100256 AACH63_RS01895 WP_185767512.1 369455..371905(+) (clpC) [Lactococcus formosensis strain L21-20]
MKFNEKDYTPQVIRVLEKSVDYAHKFNYAWVESSHLLAALAEVPASLAFTLLNSEKIDLEEMLIDIEDFSSQVKTKKSEI
KLSPRVEAIIEQARALAQNNDKNRIGTEHLLYMLLANDAGFAGQLLREQNINIVNLRKKLEQKAYLRVPERRKAVTPASK
RNLSGKVSETTTTPTLDTVSTDLTKAAREGKLDPMIGREREVERLIHILSRRTKNNPVLVGEPGVGKSAIIEGFATRVAA
GDVPVGLRGSRIMALNMAMVVAGTKFRGEFEDRLTAIVDEVTHDKDVIVFIDELHTIIGAGGGMDSVNDASNILKPALAR
GEFQLIGATTYQEYQKYIEKDEALERRFARVNVEEPSEDETVAILQGLKEKFEAYHAVKFEEGTLERAVSLSNRYMPSRR
LPDKAIDLLDEAAAKVKITSKTNYTKLDELKAELKAEELRLQKAVVALDIVEAQGIEKDIEKLTHKIDNFTVSENDNPLV
EESDVYAVVSNLTGIPLQQMTKTESERLINLEKELHKRVVGQEEAISAVSRAIRRARSGIADTRRPLGSFMFLGPTGVGK
TELAKALAESVFGSEENMIRVDMSEFMEKFSTSRLIGAPPGYVGYDEGGQLTEQVRNKPYSVILLDEVEKAHPDIFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATAIRDDKTVGFGAKSISTDYAAMKARIMEELKKQYRPEFLNRIDETIVF
HSLTEKEIEQVVKIMSKSLVSRLKDQNIKVKFTPAALKVIADKGFDPEYGARPLRKALQREVEDTLSEQLLAGEIHPGDT
ISIGSSNKKIRISVID

Nucleotide

• Length: 2451 bp

>NTDB_id=100256 AACH63_RS01895 WP_185767512.1 369455..371905(+) (clpC) [Lactococcus formosensis strain L21-20]
ATGAAATTTAATGAAAAGGACTATACACCACAAGTCATAAGAGTGCTTGAGAAGTCTGTTGACTATGCGCATAAGTTTAA
CTACGCTTGGGTTGAAAGCTCGCACTTATTGGCTGCCTTAGCTGAGGTCCCGGCTTCATTGGCATTTACGCTACTTAATT
CAGAAAAAATTGATTTGGAAGAAATGTTAATCGACATTGAAGATTTTTCAAGTCAAGTGAAGACGAAGAAATCAGAAATA
AAGCTTAGCCCAAGAGTTGAGGCAATTATTGAACAAGCACGTGCATTGGCTCAAAACAACGATAAAAACCGTATCGGGAC
AGAGCATCTCTTGTATATGCTTTTAGCAAATGATGCTGGCTTTGCAGGACAACTTTTACGTGAGCAAAACATCAATATCG
TTAACCTCCGCAAAAAGCTAGAGCAAAAAGCATATCTACGTGTACCAGAACGCCGTAAAGCGGTGACACCAGCTTCGAAA
AGAAACTTGTCAGGGAAAGTTTCCGAAACCACGACAACGCCTACTTTAGACACGGTATCGACAGATTTGACAAAAGCAGC
CCGTGAAGGCAAGCTTGATCCAATGATTGGAAGAGAGCGAGAAGTCGAACGCCTCATCCACATTTTGAGTCGTCGGACAA
AGAATAATCCTGTTCTTGTTGGTGAACCTGGTGTTGGTAAGTCAGCGATTATTGAAGGCTTTGCGACGCGTGTGGCTGCA
GGGGATGTTCCTGTAGGTTTGCGTGGCAGTCGTATCATGGCCTTGAATATGGCGATGGTTGTTGCGGGGACAAAATTCCG
TGGTGAATTTGAAGACCGTTTGACAGCTATCGTTGATGAAGTGACACATGATAAAGATGTGATTGTCTTTATCGATGAAC
TTCATACCATTATCGGTGCTGGTGGAGGCATGGATTCTGTTAATGATGCTTCCAACATCTTAAAACCGGCATTAGCACGT
GGTGAGTTTCAACTTATTGGGGCAACAACTTATCAAGAATATCAAAAATATATTGAAAAAGATGAGGCCCTAGAACGTCG
TTTTGCCCGTGTTAATGTTGAAGAACCATCAGAAGATGAAACAGTTGCAATCTTACAAGGGTTAAAAGAAAAATTTGAAG
CTTACCATGCGGTCAAATTTGAAGAGGGAACTTTGGAGCGTGCCGTCAGTCTGAGCAATCGTTATATGCCAAGTCGTCGT
CTGCCAGATAAAGCAATTGATCTCCTTGATGAAGCCGCAGCCAAAGTTAAAATTACGAGTAAAACAAATTACACCAAGCT
TGACGAATTAAAAGCAGAGTTAAAAGCAGAAGAGCTGAGATTACAAAAAGCAGTTGTAGCACTTGATATTGTTGAAGCAC
AGGGGATTGAAAAAGATATTGAAAAGTTAACGCATAAAATTGATAACTTTACAGTATCGGAAAATGATAATCCTTTGGTT
GAGGAAAGCGATGTTTATGCTGTCGTTTCCAACCTTACAGGGATTCCTCTCCAACAGATGACGAAAACAGAAAGTGAACG
TCTGATTAATCTAGAAAAAGAGTTACATAAGCGTGTAGTTGGTCAGGAAGAAGCGATATCGGCTGTTTCTCGTGCCATAA
GACGTGCACGTTCAGGTATCGCCGATACGAGACGCCCTTTGGGTTCATTTATGTTCCTTGGTCCGACAGGGGTTGGGAAG
ACAGAGCTTGCTAAGGCTTTAGCGGAAAGTGTTTTTGGCAGTGAAGAAAACATGATTCGCGTAGACATGAGTGAATTTAT
GGAAAAATTCTCGACATCACGCCTGATTGGAGCGCCTCCAGGCTACGTAGGTTATGATGAAGGGGGACAACTAACAGAGC
AAGTCCGTAATAAGCCTTATTCTGTTATCCTTCTTGATGAAGTCGAAAAGGCCCATCCTGATATTTTCAATATCATGTTA
CAAATTCTAGATGATGGTTTCGTTACAGACACGAAGGGTCGTAAAGTTGATTTCAGAAATACGATTATCATTATGACATC
TAACCTTGGTGCAACAGCTATTCGTGATGATAAAACAGTTGGTTTTGGTGCCAAATCAATCTCAACAGACTATGCAGCTA
TGAAAGCGAGAATCATGGAAGAGCTGAAGAAACAGTACCGTCCAGAATTTCTCAATCGTATCGATGAAACTATCGTTTTC
CATTCACTGACAGAAAAAGAGATTGAACAAGTCGTGAAAATTATGAGTAAATCTCTCGTATCACGCTTGAAAGATCAAAA
TATCAAAGTGAAATTTACACCTGCTGCTTTGAAAGTTATTGCTGATAAAGGATTTGATCCTGAATACGGTGCCCGCCCAT
TGCGTAAAGCTCTGCAACGTGAGGTTGAAGACACGCTCAGTGAGCAATTGCTTGCCGGCGAAATTCATCCGGGGGATACG
ATTTCTATTGGTTCTTCTAATAAAAAGATTAGAATAAGTGTTATTGATTGA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-349)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (22-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• AAA lid domain (AAA_lid_9) (357-445)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	71.166	99.877	0.711
clpC	Streptococcus thermophilus LMG 18311	49.11	100	0.507
clpC	Streptococcus thermophilus LMD-9	49.11	100	0.507
clpC	Streptococcus pneumoniae TIGR4	49.395	100	0.5
clpC	Streptococcus pneumoniae Rx1	49.274	100	0.499
clpC	Streptococcus pneumoniae D39	49.274	100	0.499
clpC	Streptococcus mutans UA159	47.368	100	0.485
clpC	Bacillus subtilis subsp. subtilis str. 168	48.439	98.162	0.475
clpE	Streptococcus mutans UA159	46.719	78.431	0.366