Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   AACH29_RS09385 Genome accession   NZ_AP027239
Coordinates   1859156..1860199 (-) Length   347 a.a.
NCBI ID   WP_014025492.1    Uniprot ID   F9VG93
Organism   Lactococcus garvieae strain L21-12     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1854156..1865199
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AACH29_RS09370 (LG21E12_18300) rpsB 1854190..1854963 (-) 774 WP_014025489.1 30S ribosomal protein S2 -
  AACH29_RS09375 (LG21E12_18310) - 1855236..1856276 (+) 1041 WP_014025490.1 lactonase family protein -
  AACH29_RS09380 (LG21E12_18320) adhE 1856432..1859125 (+) 2694 WP_014025491.1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase -
  AACH29_RS09385 (LG21E12_18330) sepM 1859156..1860199 (-) 1044 WP_014025492.1 SepM family pheromone-processing serine protease Regulator
  AACH29_RS09390 (LG21E12_18340) coaD 1860189..1860686 (-) 498 WP_014025493.1 pantetheine-phosphate adenylyltransferase -
  AACH29_RS09395 (LG21E12_18350) rsmD 1860676..1861215 (-) 540 WP_014025494.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  AACH29_RS09400 (LG21E12_18360) - 1861310..1862656 (-) 1347 WP_003133148.1 glucose-6-phosphate isomerase -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 37776.10 Da        Isoelectric Point: 6.9820

>NTDB_id=100237 AACH29_RS09385 WP_014025492.1 1859156..1860199(-) (sepM) [Lactococcus garvieae strain L21-12]
MKNEKIKKHKKLKLFFAIALPLLIVVGLFFPLPYYIEQPGGTIPVNQMVDVAGKKDEHKGNFYLTTVEMVQANAASMLYS
KSNSFATILSSEEMTGGMTNQQFDLVNQFYMQTAQNTAVYQAFKLAGKPYEMKYQGVYVLSITEDSTFKNDLQLSDTITA
VNGHTFKSSTDMIDYVSQQKVGDEVTIKYTRMDGSNHEATGKYIKLSNGKTGIGIGLVDHTQVVTDPKVKIDAGSIGGPS
AGMMFTLEIYSQITGKDLRQGREIAGTGTINEDGSIGQIGGVDKKVATASNSGAKIFLCPDETEEQAKASGTTNNYTAAL
AAAKKLNTDMKIVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=100237 AACH29_RS09385 WP_014025492.1 1859156..1860199(-) (sepM) [Lactococcus garvieae strain L21-12]
ATGAAAAATGAAAAAATAAAAAAGCATAAAAAACTAAAGCTATTCTTTGCCATCGCGTTACCGCTTCTTATTGTAGTGGG
TTTGTTCTTCCCCTTACCTTACTATATCGAGCAGCCCGGAGGAACCATTCCAGTTAATCAGATGGTCGATGTTGCGGGAA
AGAAAGATGAACATAAAGGCAATTTTTATTTAACGACTGTTGAAATGGTGCAGGCCAATGCCGCAAGTATGCTTTATTCC
AAGTCGAACTCTTTTGCCACTATTTTGAGTAGTGAAGAGATGACGGGTGGGATGACTAATCAGCAATTTGACTTGGTCAA
CCAGTTCTATATGCAGACCGCGCAAAATACAGCTGTTTATCAGGCCTTTAAGTTGGCAGGGAAACCTTATGAGATGAAGT
ATCAAGGGGTCTACGTTTTGAGTATCACTGAGGATTCGACATTTAAAAATGACTTGCAACTTTCGGATACGATAACGGCA
GTTAATGGCCACACTTTCAAATCTTCAACTGATATGATTGACTATGTGTCTCAACAAAAAGTTGGAGATGAGGTGACCAT
CAAGTACACACGGATGGATGGCAGCAACCATGAAGCCACAGGAAAGTACATTAAGTTGAGTAATGGTAAAACAGGGATTG
GTATTGGTTTAGTAGATCATACACAGGTTGTGACAGACCCTAAAGTTAAGATCGATGCCGGAAGTATTGGCGGGCCAAGT
GCTGGGATGATGTTTACCTTGGAAATATATAGCCAAATCACAGGCAAAGATTTACGTCAAGGACGCGAAATTGCAGGTAC
TGGAACGATCAATGAAGATGGCAGCATCGGGCAAATAGGTGGTGTTGATAAAAAAGTTGCTACAGCAAGCAATTCGGGTG
CAAAAATTTTCCTTTGCCCGGATGAAACGGAAGAACAGGCAAAGGCTTCGGGTACAACAAATAACTATACAGCTGCGCTT
GCGGCAGCTAAAAAGTTGAATACAGATATGAAAATCGTACCTGTAAAGACGATCCAAGATGCACTAGACTATCTCGAAAA
ATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(134-194)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(229-308)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9VG93

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.991

100

0.49

Multiple sequence alignment