Detailed information NTG0100233

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: AACH29_RS08625
• Genome accession: NZ_AP027239
• Coordinates: 1711277..1712212 (-)
• Length: 311 a.a.
• NCBI ID: WP_014025404.1
• Uniprot ID: A0A6L2ZWA9
• Organism: Lactococcus garvieae strain L21-12
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1706277..1717212

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AACH29_RS08600 (LG21E12_16940)	-	1706325..1707185 (-)	861	WP_014025402.1	S1 RNA-binding domain-containing protein	-
AACH29_RS08605 (LG21E12_16950)	frr	1707293..1707850 (-)	558	WP_003133324.1	ribosome recycling factor	-
AACH29_RS08610 (LG21E12_16960)	pyrH	1707880..1708596 (-)	717	WP_003133322.1	UMP kinase	-
AACH29_RS08615 (LG21E12_16970)	-	1708687..1709880 (-)	1194	WP_003133320.1	acetate kinase	-
AACH29_RS08620 (LG21E12_16980)	-	1709999..1711192 (-)	1194	WP_014025403.1	acetate kinase	-
AACH29_RS08625 (LG21E12_16990)	comYH	1711277..1712212 (-)	936	WP_014025404.1	class I SAM-dependent methyltransferase	Machinery gene
AACH29_RS08630 (LG21E12_17000)	-	1712258..1712488 (-)	231	WP_003133314.1	DUF3165 family protein	-
AACH29_RS08635 (LG21E12_17010)	typA	1712563..1714404 (-)	1842	WP_003133313.1	translational GTPase TypA	-
AACH29_RS08640 (LG21E12_17020)	-	1714725..1714937 (+)	213	WP_003133311.1	YqgQ family protein	-
AACH29_RS08645 (LG21E12_17030)	-	1714930..1715895 (+)	966	WP_014025405.1	ROK family glucokinase	-
AACH29_RS08650 (LG21E12_17040)	-	1715915..1716295 (+)	381	WP_003133308.1	rhodanese-like domain-containing protein	-
AACH29_RS08655 (LG21E12_17050)	-	1716335..1716781 (-)	447	WP_003133306.1	Dps family protein	-

Sequence

Protein

• Length: 311 a.a.
• Molecular weight: 35138.19 Da
• Isoelectric Point: 4.6737

>NTDB_id=100233 AACH29_RS08625 WP_014025404.1 1711277..1712212(-) (comYH) [Lactococcus garvieae strain L21-12]
MDIEKIEKAFGLVLENIMAIQAELLTDFYDAFVEQNAAYLGALEFASLTKENNDKVRSMNLTKSEWQKLFQFVLLQGSRV
APMQANHNLTPDSIGFIFNFIIEELHKERKIRVLEFGSGTGNLAETLLVHMQKEVDYVGFEVDDLLLDLSASMSEVMGTE
ASFLQIDAVKPQPLESVDVVMSDLPVGYYPDDETARHFQVHDKSEHTYVHHLMIEQSFKYLKESGFALFLAPDNLLTSAQ
SEFLKAWIKEHAHVAAVITLPSSLFKGAGKSIYLLSKNQTNTPTFVYPLADLADRSILQEFMSEFVKNVKI

Nucleotide

• Length: 936 bp

>NTDB_id=100233 AACH29_RS08625 WP_014025404.1 1711277..1712212(-) (comYH) [Lactococcus garvieae strain L21-12]
ATGGATATAGAGAAAATCGAAAAAGCCTTTGGATTGGTTCTTGAAAATATTATGGCAATTCAAGCGGAGCTCTTGACGGA
TTTTTATGATGCTTTTGTGGAACAAAATGCAGCTTACTTAGGCGCTTTAGAGTTTGCATCTCTGACGAAGGAAAATAATG
ATAAGGTTCGTTCAATGAACCTCACGAAAAGTGAGTGGCAAAAGCTGTTTCAGTTTGTCTTGCTTCAAGGGTCACGTGTC
GCACCAATGCAAGCAAATCATAATTTAACACCAGATTCTATTGGGTTTATCTTTAATTTTATCATTGAAGAGTTGCACAA
AGAAAGAAAGATTCGTGTACTAGAATTTGGCTCAGGAACAGGGAATTTAGCGGAAACGCTCTTGGTTCACATGCAAAAAG
AAGTAGACTATGTTGGTTTTGAAGTAGATGACCTCTTGTTGGATTTGTCCGCTTCAATGTCAGAAGTCATGGGAACAGAA
GCAAGTTTTCTCCAAATTGACGCCGTGAAACCACAGCCCTTGGAGTCTGTAGATGTTGTGATGAGTGATCTCCCGGTTGG
TTATTATCCAGACGATGAAACTGCTCGCCATTTTCAAGTGCATGACAAATCAGAACATACCTATGTGCACCACTTAATGA
TTGAGCAATCCTTTAAGTATCTGAAGGAGAGTGGTTTTGCGCTCTTCTTAGCTCCAGATAATCTTTTGACAAGTGCACAG
TCAGAATTTTTGAAGGCTTGGATTAAAGAACATGCACATGTTGCTGCAGTCATTACATTGCCTTCGTCACTCTTTAAAGG
TGCAGGAAAATCGATTTATTTATTAAGTAAAAACCAAACAAATACACCAACTTTTGTTTACCCCTTGGCTGATTTAGCAG
ACCGTTCTATTTTGCAAGAATTTATGTCTGAGTTTGTGAAAAATGTCAAGATTTGA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (132-286)

3D structure

• AlphaFold DB: A0A6L2ZWA9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA140	49.677	99.678	0.495
comYH	Streptococcus mutans UA159	49.355	99.678	0.492