Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | QQ680_RS00280 | Genome accession | NZ_CP156697 |
| Coordinates | 62351..63979 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain R8014 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 57130..100854 | 62351..63979 | within | 0 |
| SCCmec | 44033..65350 | 62351..63979 | within | 0 |
Gene organization within MGE regions
Location: 44033..100854
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QQ680_RS00185 (QQ680_000185) | mecA | 44033..46042 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| QQ680_RS00190 (QQ680_000190) | mecR1 | 46139..47896 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| QQ680_RS00195 (QQ680_000195) | mecI | 47896..48267 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| QQ680_RS00200 (QQ680_000200) | psm-mec | 48352..48420 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| QQ680_RS00205 (QQ680_000205) | - | 48754..49884 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| QQ680_RS00210 (QQ680_000210) | cstB | 49998..51332 (-) | 1335 | Protein_39 | persulfide dioxygenase-sulfurtransferase CstB | - |
| QQ680_RS00215 (QQ680_000215) | - | 51365..52429 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| QQ680_RS00220 (QQ680_000220) | cstR | 52565..52825 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| QQ680_RS00225 (QQ680_000225) | - | 52825..53463 (+) | 639 | Protein_42 | sulfite exporter TauE/SafE family protein | - |
| QQ680_RS00230 (QQ680_000230) | - | 53808..54470 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| QQ680_RS00235 (QQ680_000235) | erm(A) | 54956..55687 (+) | 732 | WP_285238787.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| QQ680_RS00240 (QQ680_000240) | - | 55813..56595 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| QQ680_RS00245 (QQ680_000245) | - | 56746..57123 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| QQ680_RS00250 (QQ680_000250) | - | 57130..59022 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| QQ680_RS00255 (QQ680_000255) | - | 59019..60104 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| QQ680_RS00260 (QQ680_000260) | - | 60223..60540 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| QQ680_RS00265 (QQ680_000265) | - | 60561..61067 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| QQ680_RS00270 (QQ680_000270) | - | 61085..61396 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| QQ680_RS00275 (QQ680_000275) | - | 61483..61833 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| QQ680_RS00280 (QQ680_000280) | ccrB | 62351..63979 (-) | 1629 | WP_001186602.1 | recombinase family protein | Machinery gene |
| QQ680_RS00285 (QQ680_000285) | ccrA | 64001..65350 (-) | 1350 | WP_000815646.1 | recombinase family protein | Machinery gene |
| QQ680_RS00290 (QQ680_000290) | - | 65584..67377 (-) | 1794 | WP_000195105.1 | DUF927 domain-containing protein | - |
| QQ680_RS00295 (QQ680_000295) | - | 67377..67673 (-) | 297 | WP_000273824.1 | single-stranded DNA-binding protein | - |
| QQ680_RS00300 (QQ680_000300) | - | 67866..68912 (-) | 1047 | WP_001060127.1 | hypothetical protein | - |
| QQ680_RS00305 (QQ680_000305) | - | 69163..70304 (-) | 1142 | Protein_58 | IS3-like element ISSau4 family transposase | - |
| QQ680_RS00310 (QQ680_000310) | - | 70815..71741 (-) | 927 | Protein_59 | YfcC family protein | - |
| QQ680_RS00315 (QQ680_000315) | - | 72463..73158 (-) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| QQ680_RS00320 (QQ680_000320) | - | 73133..75802 (-) | 2670 | WP_000446429.1 | sensor histidine kinase KdpD | - |
| QQ680_RS00325 (QQ680_000325) | kdpF | 75969..76049 (+) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| QQ680_RS00330 (QQ680_000330) | kdpA | 76070..77746 (+) | 1677 | WP_000029430.1 | potassium-transporting ATPase subunit KdpA | - |
| QQ680_RS00335 (QQ680_000335) | - | 77765..79786 (+) | 2022 | WP_285238788.1 | K(+)-transporting ATPase subunit B | - |
| QQ680_RS00340 (QQ680_000340) | - | 79802..80359 (+) | 558 | WP_001193482.1 | K(+)-transporting ATPase subunit C | - |
| QQ680_RS00345 (QQ680_000345) | - | 80904..81773 (-) | 870 | WP_000626133.1 | hypothetical protein | - |
| QQ680_RS00350 (QQ680_000350) | - | 81783..82679 (-) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| QQ680_RS00355 (QQ680_000355) | - | 83798..84424 (-) | 627 | WP_001176969.1 | hypothetical protein | - |
| QQ680_RS00360 (QQ680_000360) | - | 84539..86047 (+) | 1509 | WP_001001347.1 | protein kinase | - |
| QQ680_RS00365 (QQ680_000365) | - | 86296..86430 (-) | 135 | WP_001790628.1 | hypothetical protein | - |
| QQ680_RS00370 (QQ680_000370) | - | 86394..86486 (+) | 93 | WP_001790000.1 | hypothetical protein | - |
| QQ680_RS00375 (QQ680_000375) | - | 86633..88378 (+) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| QQ680_RS00380 (QQ680_000380) | - | 88476..88831 (-) | 356 | Protein_73 | tRNA-dihydrouridine synthase | - |
| QQ680_RS00385 (QQ680_000385) | - | 89136..89224 (-) | 89 | Protein_74 | hypothetical protein | - |
| QQ680_RS00390 (QQ680_000390) | - | 89322..90077 (-) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| QQ680_RS00395 (QQ680_000395) | cstR | 90077..90337 (-) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| QQ680_RS00400 (QQ680_000400) | cstA | 90474..91538 (+) | 1065 | WP_000816133.1 | persulfide response sulfurtransferase CstA | - |
| QQ680_RS00405 (QQ680_000405) | cstB | 91569..92903 (+) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| QQ680_RS00410 (QQ680_000410) | sqr | 92922..94115 (+) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| QQ680_RS00415 (QQ680_000415) | - | 94382..94596 (-) | 215 | Protein_80 | universal stress protein | - |
| QQ680_RS00420 (QQ680_000420) | - | 94782..95768 (-) | 987 | WP_000662022.1 | tRNA-dihydrouridine synthase | - |
| QQ680_RS00425 (QQ680_000425) | - | 96077..96280 (+) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| QQ680_RS00430 (QQ680_000430) | - | 96329..96625 (+) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| QQ680_RS00435 (QQ680_000435) | - | 96833..97435 (+) | 603 | WP_000908956.1 | hypothetical protein | - |
| QQ680_RS00440 (QQ680_000440) | - | 97702..100854 (+) | 3153 | WP_285238789.1 | DEAD/DEAH box helicase | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=1002273 QQ680_RS00280 WP_001186602.1 62351..63979(-) (ccrB) [Staphylococcus aureus strain R8014]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=1002273 QQ680_RS00280 WP_001186602.1 62351..63979(-) (ccrB) [Staphylococcus aureus strain R8014]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |