Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   AACH29_RS02215 Genome accession   NZ_AP027239
Coordinates   449510..450205 (+) Length   231 a.a.
NCBI ID   WP_004259096.1    Uniprot ID   -
Organism   Lactococcus garvieae strain L21-12     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 444510..455205
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AACH29_RS02190 (LG21E12_04260) - 444743..445444 (+) 702 WP_004259114.1 DeoR/GlpR family DNA-binding transcription regulator -
  AACH29_RS02195 (LG21E12_04270) pfkB 445441..446367 (+) 927 WP_004259111.1 1-phosphofructokinase -
  AACH29_RS02200 (LG21E12_04280) - 446382..448286 (+) 1905 WP_014024348.1 fructose-specific PTS transporter subunit EIIC -
  AACH29_RS02205 (LG21E12_04290) - 448398..448640 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  AACH29_RS02210 (LG21E12_04300) - 448857..449408 (+) 552 WP_014024349.1 YceD family protein -
  AACH29_RS02215 (LG21E12_04310) covR 449510..450205 (+) 696 WP_004259096.1 response regulator transcription factor Regulator
  AACH29_RS02220 (LG21E12_04320) covS 450294..451784 (+) 1491 WP_014024351.1 HAMP domain-containing histidine kinase Regulator
  AACH29_RS02225 (LG21E12_04330) - 452181..453752 (+) 1572 WP_014024352.1 ABC transporter permease subunit -
  AACH29_RS02230 (LG21E12_04340) - 453753..454490 (+) 738 WP_014024353.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 26979.74 Da        Isoelectric Point: 5.4730

>NTDB_id=100218 AACH29_RS02215 WP_004259096.1 449510..450205(+) (covR) [Lactococcus garvieae strain L21-12]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQGNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTIEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=100218 AACH29_RS02215 WP_004259096.1 449510..450205(+) (covR) [Lactococcus garvieae strain L21-12]
ATGAATTCATCTAAACGTATTTTGATTATCGAAGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGATACCAAACTGCGGTTCAAGGCAATGGTCGTAAAGGTCTTGAAGAAGCAATGTCAAAAGATTATGATTTGATTTTGC
TTGACTTAATGCTCCCAGAGCTTGATGGCTTTGAGGTTGCACGACGCTTACGCCGTGAGAAAGATACACATATTATTATG
ATGACTGCACGTGATTCGACAATGGACCGTGTAGCAGGGCTTGATATTGGCGCAGATGACTATATTACAAAACCATTTGC
TATTGAAGAATTGTTAGCGCGTGTCCGCTCACTCTTCCGTCGTGAAGATCATATCCACACGATTGAAAAGTCAGACAATA
CTTCATTCCGTGATTTGGTAATTGATAAGACCAACCGTACTGTACACCGTGGAAAAAAAGTTATTGACCTTACACGCCGT
GAGTACGATTTGCTTTTGACACTGATGCAAAATGTAGGTGATGTCGTAACACGTGAATACTTGGTTTCTGAAGTATGGGG
TTACGAAGAAGGTACAGAAACAAACGTTGTGGACGTTTATATCCGTTATCTGCGTAACAAAATTGACGTGGAGGGCCGTG
AAAGCTATATCCAAACGGTTCGTGGTATGGGATATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(7-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

87.773

99.134

0.87
  covR Streptococcus salivarius strain HSISS4

66.81

100

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424

Multiple sequence alignment