Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   EL147_RS10365 Genome accession   NZ_LR134341
Coordinates   2115583..2117682 (-) Length   699 a.a.
NCBI ID   WP_007894268.1    Uniprot ID   G5K704
Organism   Streptococcus pseudoporcinus strain NCTC13786     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 2110583..2122682
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL147_RS10335 (NCTC13786_02081) - 2111018..2111857 (+) 840 WP_007894363.1 thymidylate synthase -
  EL147_RS10340 (NCTC13786_02082) - 2111937..2112434 (+) 498 WP_007894152.1 dihydrofolate reductase -
  EL147_RS10345 (NCTC13786_02083) - 2112459..2112629 (+) 171 WP_003083300.1 hypothetical protein -
  EL147_RS10350 (NCTC13786_02084) clpX 2112660..2113889 (+) 1230 WP_037598846.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  EL147_RS10355 (NCTC13786_02085) yihA 2113902..2114501 (+) 600 WP_007894077.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  EL147_RS10360 (NCTC13786_02086) - 2114623..2115339 (+) 717 WP_007894313.1 hypothetical protein -
  EL147_RS10365 (NCTC13786_02087) clpE 2115583..2117682 (-) 2100 WP_007894268.1 AAA family ATPase Regulator
  EL147_RS10370 (NCTC13786_02089) rplJ 2118089..2118589 (+) 501 WP_003083012.1 50S ribosomal protein L10 -
  EL147_RS10375 rplL 2118655..2119020 (+) 366 WP_007894316.1 50S ribosomal protein L7/L12 -
  EL147_RS10380 (NCTC13786_02091) - 2119219..2119392 (+) 174 WP_001168336.1 hypothetical protein -
  EL147_RS10385 (NCTC13786_02092) - 2119389..2120207 (+) 819 WP_000822785.1 replication initiator protein A -
  EL147_RS10395 (NCTC13786_02094) dcm 2120356..2121711 (+) 1356 WP_000670052.1 DNA (cytosine-5-)-methyltransferase -
  EL147_RS10400 (NCTC13786_02095) - 2121695..2122123 (+) 429 WP_001050386.1 hypothetical protein -
  EL147_RS10405 (NCTC13786_02096) - 2122134..2122517 (+) 384 WP_000895333.1 hypothetical protein -

Sequence

Protein


Download         Length: 699 a.a.        Molecular weight: 77411.58 Da        Isoelectric Point: 5.4065

>NTDB_id=1002154 EL147_RS10365 WP_007894268.1 2115583..2117682(-) (clpE) [Streptococcus pseudoporcinus strain NCTC13786]
MTKNYGRDSFGNMDDIFNQLMGNIGGYQTENRRYLVNGREMTPEEFNHYRQTGKIPNQISNETGHSKQQAASNGILEKLG
TNLTEEARKGNLDPVIGRNKEIQDTAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVAGDVPTAIKGKEIISIDISSL
EAGTQYRGSFEENIQQLITEVKESGNIVLFFDEIHQILGAGSTGGESGSKGLADILKPALSRGEITVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPNAEDTFHILMGIRNLYEQHHNVILPDSVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAA
QHPATDLQSLEKEIETQKKAQEQAVEKEDFEAALKAKTRIEELQKQIENHTEGQKVTANINDIAQSVERLTGIPVSKMGA
SDLERLKEIASRLKAHVIGQDQAVSAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGSKESIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNKNTLTEKVRRNPYAIILLDEIEKADSQVITLLLQVLDDGRLTDGQGNTIDFKNT
VIIATSNAGFGYEHNLDKQDKEIPIMDRLAPYFRPEFLNRFNALIEFKSLTKDDLKAIVNLMLAEVDKTIVKKGITLEVD
DDVKDHLIELGYDPTMGVRPLRRVIEQEIRDNITDYYLDHPEAKKLHAQLKNGKITITP

Nucleotide


Download         Length: 2100 bp        

>NTDB_id=1002154 EL147_RS10365 WP_007894268.1 2115583..2117682(-) (clpE) [Streptococcus pseudoporcinus strain NCTC13786]
ATGACAAAAAATTATGGAAGAGATTCTTTTGGAAATATGGATGATATTTTCAATCAACTAATGGGAAATATTGGTGGTTA
CCAGACAGAAAATCGTCGCTATTTGGTCAATGGTCGTGAGATGACTCCGGAAGAGTTCAATCACTATCGCCAAACTGGTA
AGATACCAAATCAAATAAGTAATGAGACTGGCCATTCTAAACAACAAGCGGCTAGTAACGGTATTTTGGAAAAATTAGGA
ACCAATCTAACGGAAGAAGCTCGCAAAGGAAATCTAGATCCTGTTATTGGACGCAATAAGGAAATTCAAGATACTGCTGA
AATTCTATCTCGACGAACAAAAAATAATCCTGTTCTGGTTGGTGATGCGGGAGTTGGAAAAACTGCTGTTGTTGAAGGCT
TAGCTCAGGCTATTGTAGCTGGGGATGTCCCAACTGCGATTAAAGGGAAAGAAATCATTTCAATTGATATTTCTAGTCTA
GAAGCAGGTACCCAATACCGTGGTAGTTTTGAAGAAAATATTCAGCAGTTAATTACTGAAGTTAAAGAATCAGGTAATAT
TGTCCTATTCTTTGATGAAATTCATCAAATTTTAGGAGCAGGCTCTACAGGTGGCGAATCTGGATCTAAAGGTTTAGCTG
ATATCCTTAAACCCGCCTTATCACGTGGAGAAATAACAGTCATCGGTGCGACAACTCAAGATGAATATCGAAATACTATC
CTTAAAAATGCTGCTTTAGCAAGACGCTTTAATGAAGTTAAGGTCAATGCTCCAAATGCTGAGGACACTTTCCATATCTT
AATGGGAATACGAAATCTCTATGAACAACATCATAATGTTATTCTTCCCGACTCCGTATTAAAGGCAGCAGTTGATTATT
CTATCCAGTATATTCCACAGCGTAGCCTCCCTGATAAGGCTATTGATTTATTAGATATGACAGCTGCACATTTAGCTGCC
CAACATCCAGCGACAGATCTTCAATCCCTCGAAAAAGAAATTGAAACACAAAAAAAGGCTCAAGAACAGGCTGTAGAAAA
AGAAGACTTTGAAGCAGCTCTCAAAGCAAAAACTAGAATTGAAGAATTGCAAAAACAGATTGAAAACCATACAGAAGGTC
AAAAAGTGACTGCCAATATTAATGACATCGCTCAATCTGTTGAACGACTAACCGGAATCCCTGTTTCCAAGATGGGCGCA
AGTGATTTAGAACGTCTAAAAGAAATTGCTAGCCGCTTAAAAGCACATGTCATCGGTCAAGATCAAGCTGTTTCTGCGGT
TGCAAGAGCTATTCGTCGGAACCGGGCTGGCTTTGATGAGGGGAATCGTCCCATTGGATCCTTCTTATTTGTAGGACCGA
CTGGGGTTGGGAAAACTGAACTCGCAAAACAGCTCGCGCTTGATATGTTTGGATCTAAAGAGTCCATTATAAGATTAGAT
ATGTCAGAATACAGTGACCGAACAGCTGTTTCAAAATTAATTGGTACTACTGCTGGTTATGTGGGCTATGATGATAACAA
AAATACCTTAACTGAGAAAGTACGTCGTAATCCCTATGCCATTATCCTTTTGGACGAAATTGAAAAAGCTGACTCACAAG
TTATTACGCTCTTACTTCAAGTTTTAGATGATGGTCGTCTGACAGATGGACAGGGAAATACCATTGACTTCAAAAACACT
GTTATTATTGCCACATCCAATGCTGGATTTGGTTATGAGCATAACCTTGACAAGCAAGACAAAGAAATACCAATCATGGA
CCGACTTGCGCCCTACTTTAGACCAGAATTTCTTAATAGATTCAATGCTCTTATAGAATTCAAGAGTTTGACAAAAGATG
ATCTGAAAGCTATCGTCAATCTGATGTTAGCCGAAGTTGATAAGACGATTGTAAAAAAAGGAATCACATTAGAAGTAGAT
GACGATGTTAAAGATCACCTAATTGAGCTTGGCTATGATCCAACAATGGGAGTTCGTCCACTTAGACGTGTTATCGAACA
AGAAATTCGTGACAATATTACAGATTACTACTTAGACCATCCTGAAGCCAAAAAACTCCATGCTCAGTTGAAAAATGGAA
AGATTACCATTACTCCATAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-681)

AAA lid domain (AAA_lid_9)

(260-355)

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-602)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5K704

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

50.858

91.702

0.466
  clpE Streptococcus pneumoniae TIGR4

50.237

90.558

0.455
  clpE Streptococcus pneumoniae Rx1

50.237

90.558

0.455
  clpE Streptococcus pneumoniae D39

50.237

90.558

0.455
  clpE Streptococcus pneumoniae R6

50.237

90.558

0.455
  clpC Lactococcus lactis subsp. cremoris KW2

50.079

90.558

0.454
  clpC Bacillus subtilis subsp. subtilis str. 168

44.79

91.989

0.412
  clpC Streptococcus pneumoniae Rx1

42.383

94.85

0.402
  clpC Streptococcus pneumoniae D39

42.383

94.85

0.402
  clpC Streptococcus pneumoniae TIGR4

42.383

94.85

0.402
  clpC Streptococcus thermophilus LMD-9

43.569

88.984

0.388
  clpC Streptococcus mutans UA159

42.188

91.559

0.386
  clpC Streptococcus thermophilus LMG 18311

43.408

88.984

0.386
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

40.429

93.419

0.378

Multiple sequence alignment