Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexA   Type   Machinery gene
Locus tag   EL147_RS06310 Genome accession   NZ_LR134341
Coordinates   1284794..1287343 (+) Length   849 a.a.
NCBI ID   WP_007893751.1    Uniprot ID   G5K7H6
Organism   Streptococcus pseudoporcinus strain NCTC13786     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1279794..1292343
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL147_RS06285 (NCTC13786_01258) - 1280181..1281065 (+) 885 WP_007893787.1 YitT family protein -
  EL147_RS06290 (NCTC13786_01259) - 1281117..1281998 (+) 882 WP_007893764.1 YitT family protein -
  EL147_RS06295 (NCTC13786_01260) argS 1282044..1283732 (-) 1689 WP_007893778.1 arginine--tRNA ligase -
  EL147_RS06300 (NCTC13786_01261) argR 1284020..1284457 (+) 438 WP_007893813.1 arginine repressor -
  EL147_RS06305 (NCTC13786_01262) - 1284454..1284807 (+) 354 WP_007893906.1 YlbF family regulator -
  EL147_RS06310 (NCTC13786_01263) hexA 1284794..1287343 (+) 2550 WP_007893751.1 DNA mismatch repair protein MutS Machinery gene
  EL147_RS06315 (NCTC13786_01264) - 1287843..1290743 (-) 2901 WP_232010992.1 serum opacification factor -
  EL147_RS06320 - 1291736..1291915 (-) 180 WP_007893796.1 peptidase -

Sequence

Protein


Download         Length: 849 a.a.        Molecular weight: 94820.08 Da        Isoelectric Point: 5.0969

>NTDB_id=1002107 EL147_RS06310 WP_007893751.1 1284794..1287343(+) (hexA) [Streptococcus pseudoporcinus strain NCTC13786]
MTNPKISPGMQQYLDIKANYPDAFLLFRMGDFYELFYEDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLI
EMGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSAKPSTANNFLVAIDHDGQGYGLSYMDLATGEFFVTSLTDFTN
LSSEILNLKAKEVILGFELNEDQEKQLKQDSNLLLSYSDSCCENSDLLSPQLAPIELRVAGKLLAYVHQTQMRELSHLQK
VSHYEIKDYLQMTYSTKASLDLLENARTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIHQAAIEKRQRIIQTFLDNFI
ERADLSDSLKGVYDIERLSSRVSFGKVNPKDLLQLGQTLARVPYIKAVLESMTSTDLGELVDQIDTIPELENLIRSAIDP
EAQATISEGNIIRTGFDERLDHYRKVMKEGTGWIADIEGKERQASGINNLKIDYNKKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERYGTAELAKIEGQMLEAREESAQLEYDIFMRVRAQVETYIARLQSLAKAIATVDVLQSLAHVAEQNHYVCPQFN
QDKEVRIVDGRHAVVEKVMGVREYIPNSIHLTDQVSIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVSADQANLPLFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIQRASQNSLILFDELGRGTATYDGMALAQSIIEYIHDRVGAKTLFATHYHEL
TALSSQLEGLQNVHVATLERGGEVTFLHKISEGPADKSYGIHVAKIAGLPEGLLSRAGHILEELEGDSKRVTLANTSAVV
SQETSGNQQLALLTSEANEVIVDKLKAIDIMNLTPMEAMTILYDLKKEL

Nucleotide


Download         Length: 2550 bp        

>NTDB_id=1002107 EL147_RS06310 WP_007893751.1 1284794..1287343(+) (hexA) [Streptococcus pseudoporcinus strain NCTC13786]
ATGACCAATCCTAAAATTTCTCCTGGAATGCAACAGTATCTGGACATTAAAGCCAATTATCCAGATGCTTTTTTGCTTTT
TAGGATGGGAGATTTTTACGAACTATTTTATGAAGATGCAGTAAAAGCTGCACAGTTATTAGAAATTGGTTTAACCAGTC
GCAATAAAAACGCTGAAAATCCTATTCCCATGGCAGGAGTGCCCCATCATTCAGCTCAACAATATATTGATGTTCTCATT
GAAATGGGTTATAAGGTTGCAATTGCTGAACAGATGGAAGACCCTAAAAAAGCAGTCGGGGTGGTCAAACGTGAAGTTGT
TCAAGTTATCACTCCTGGGACAGTTGTTGATTCAGCTAAACCAAGTACAGCTAATAACTTTTTGGTTGCCATCGATCATG
ATGGACAGGGTTATGGTTTGTCCTATATGGATTTGGCAACAGGAGAATTCTTTGTAACGAGTCTGACTGACTTTACAAAC
CTTAGCAGTGAAATCCTAAATTTAAAAGCCAAAGAAGTTATTCTTGGTTTTGAACTGAATGAAGATCAAGAAAAACAATT
AAAGCAAGACAGCAACTTGCTTTTATCCTATAGTGATAGTTGCTGCGAAAATTCTGATCTACTAAGTCCGCAACTCGCTC
CAATTGAACTTAGGGTGGCAGGGAAGCTCTTGGCTTATGTTCATCAAACCCAAATGCGAGAACTCTCGCATCTACAAAAA
GTTAGCCATTATGAGATTAAAGACTATCTGCAGATGACTTATAGTACAAAAGCCAGCTTAGATTTGCTTGAAAATGCTCG
TACGGGTAAAAAACACGGGAGTCTTTACTGGCTGTTGGATGAGACGAAGACGGCTATGGGAATGCGGTTATTAAGAACTT
GGATAGATCGTCCGCTCATTCATCAGGCGGCCATTGAAAAAAGGCAAAGAATTATCCAGACCTTCCTTGATAATTTTATC
GAACGAGCTGATTTAAGTGATAGTTTAAAAGGGGTCTATGATATTGAGCGCCTGTCCAGTCGAGTTTCCTTTGGTAAGGT
CAACCCAAAAGACCTTCTTCAATTAGGTCAAACATTAGCCCGAGTTCCTTATATTAAGGCTGTTTTAGAGTCTATGACCA
GCACAGATTTAGGAGAGCTAGTCGATCAAATTGATACTATTCCAGAACTGGAAAACCTTATTCGCTCAGCTATTGACCCA
GAGGCTCAAGCCACCATTAGTGAAGGTAATATTATAAGGACCGGCTTTGATGAGCGCTTGGATCATTACCGAAAAGTGAT
GAAAGAAGGGACAGGTTGGATTGCTGATATTGAAGGCAAGGAACGCCAAGCCAGTGGTATCAATAATTTAAAAATTGATT
ACAACAAAAAAGACGGTTACTATTTCCATGTGACAAACTCTAATTTATCACTAGTTCCAGACCATTTCTTTAGAAAAGCA
ACGCTGAAAAACTCAGAACGATATGGCACAGCAGAACTCGCTAAGATTGAAGGACAGATGTTAGAGGCGCGTGAAGAATC
AGCTCAGTTAGAGTATGATATTTTCATGAGGGTTCGAGCACAGGTGGAAACTTATATTGCGCGATTGCAGAGCTTAGCCA
AAGCCATTGCAACTGTAGATGTCTTGCAAAGCCTAGCTCATGTTGCAGAGCAGAACCACTACGTTTGTCCTCAATTTAAT
CAAGATAAAGAGGTGAGGATTGTAGATGGTCGTCATGCAGTTGTTGAAAAAGTAATGGGTGTCCGGGAATACATTCCAAA
CAGTATTCACTTGACAGACCAGGTTTCTATTCAGTTAATCACTGGACCAAATATGAGTGGTAAGTCAACCTATATGCGTC
AACTTGCCTTGACTGTTATCATGGCCCAAATGGGTTCCTATGTATCTGCAGATCAGGCTAATCTCCCATTATTTGACGCT
ATCTTTACTCGAATAGGAGCTGCAGATGACTTGATTTCTGGCCAGTCAACCTTTATGGTGGAAATGATGGAAGCTAATCA
AGCTATCCAGCGTGCTAGTCAAAACTCACTTATTCTATTTGATGAGCTTGGGAGGGGAACAGCGACCTATGATGGCATGG
CCTTGGCTCAATCAATCATAGAGTATATCCATGATCGTGTTGGTGCTAAAACGCTGTTTGCAACGCATTACCATGAGTTG
ACAGCACTATCAAGTCAACTGGAAGGCCTACAAAATGTCCATGTGGCGACCTTGGAAAGAGGAGGAGAAGTGACTTTTTT
ACATAAGATTTCTGAAGGCCCTGCGGACAAGTCTTATGGTATCCACGTTGCTAAAATTGCAGGCCTCCCAGAGGGATTAC
TTTCAAGGGCAGGCCATATTTTAGAAGAATTAGAAGGTGATTCAAAAAGGGTGACCTTAGCCAATACCTCAGCAGTAGTT
TCTCAAGAGACGAGTGGTAATCAACAACTTGCTTTGTTGACAAGCGAGGCTAACGAGGTTATTGTTGACAAGCTTAAGGC
AATTGATATCATGAATCTGACTCCTATGGAAGCAATGACCATTCTTTATGACTTAAAAAAAGAATTATAA

Domains

Predicted by InterProScan.

MutS family domain IV (MutS_IV)

(415-506)

MutS domain III (MutS_III)

(256-546)

MutS domain V (MutS_V)

(599-785)

MutS domain II (MutS_II)

(126-187)

MutS domain I (MutS_I)

(8-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5K7H6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexA Streptococcus pneumoniae R6

68.508

100

0.687
  mutS Pseudomonas stutzeri strain ATCC 17587

36

100

0.371