Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   EL140_RS04965 Genome accession   NZ_LR134336
Coordinates   969572..970036 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus oralis ATCC 35037 strain NCTC 11427     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 964572..975036
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL140_RS04945 (NCTC11427_00973) - 964752..965744 (-) 993 WP_000448714.1 alpha-ketoacid dehydrogenase subunit beta -
  EL140_RS04950 (NCTC11427_00974) - 965761..966729 (-) 969 WP_000105349.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  EL140_RS04955 (NCTC11427_00975) - 966909..968249 (-) 1341 WP_000283624.1 MATE family efflux transporter -
  EL140_RS04960 (NCTC11427_00976) - 968291..969559 (-) 1269 WP_000924511.1 dihydroorotase -
  EL140_RS04965 (NCTC11427_00977) mutX 969572..970036 (-) 465 WP_001135768.1 NUDIX hydrolase Machinery gene
  EL140_RS04970 (NCTC11427_00978) - 970046..970699 (-) 654 WP_001164853.1 uracil-DNA glycosylase -
  EL140_RS04975 (NCTC11427_00979) - 970761..971453 (-) 693 WP_001146400.1 YjjG family noncanonical pyrimidine nucleotidase -
  EL140_RS04980 (NCTC11427_00980) - 971585..972679 (-) 1095 WP_001055022.1 AI-2E family transporter -
  EL140_RS04985 (NCTC11427_00981) - 972689..973978 (-) 1290 WP_000411457.1 hypothetical protein -
  EL140_RS04990 (NCTC11427_00982) - 974319..974735 (-) 417 WP_000110627.1 Imm70 family immunity protein -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=1002005 EL140_RS04965 WP_001135768.1 969572..970036(-) (mutX) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=1002005 EL140_RS04965 WP_001135768.1 969572..970036(-) (mutX) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAACGGAAAAGAACTGCTCATGCTCCATCGCAATAAGAAGCCCAACGA
TGTCCATGAAGGCAAATGGATTGGTGTGGGTGGAAAGCTAGAGCGAGGTGAGACTCCACAGGAATGTGCAGCGCGTGAAA
TCCTCGAAGAAACAGGGCTCAAAGCCAAGCCAGTACTTAAAGGTGTTATCACTTTTCCTGAATTTACGCCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACAGAGTTCGAGGGTGACTTGATTGACTGCAATGAGGGGACCTTAGAATGGGTTCC
CTATGATGAAGTCTTAAGCAAGCCAACTTGGGAGGGTGATCACACCTTTGTTGAGTGGCTTTTAGAAGATAAACCTTTCT
TTTCAGCAAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987