Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   EL130_RS02345 Genome accession   NZ_LR134320
Coordinates   450840..452795 (+) Length   651 a.a.
NCBI ID   WP_002283525.1    Uniprot ID   -
Organism   Streptococcus mutans strain NCTC10832     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 445840..457795
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL130_RS02320 (NCTC10832_00435) - 446098..446622 (+) 525 WP_002282629.1 cyclic nucleotide-binding domain-containing protein -
  EL130_RS02325 (NCTC10832_00436) argR 447019..447456 (+) 438 WP_002283527.1 arginine repressor -
  EL130_RS02330 (NCTC10832_00437) - 447453..447800 (+) 348 WP_002274702.1 YlbF family regulator -
  EL130_RS02335 (NCTC10832_00438) hexA 447793..450342 (+) 2550 WP_002283526.1 DNA mismatch repair protein MutS Machinery gene
  EL130_RS02340 - 450337..450615 (-) 279 Protein_409 transposase -
  EL130_RS02345 (NCTC10832_00439) hexB 450840..452795 (+) 1956 WP_002283525.1 DNA mismatch repair endonuclease MutL Machinery gene
  EL130_RS02350 (NCTC10832_00440) ruvA 452978..453571 (+) 594 WP_002262395.1 Holliday junction branch migration protein RuvA Machinery gene
  EL130_RS02355 (NCTC10832_00441) - 453653..454213 (+) 561 WP_002268198.1 DNA-3-methyladenine glycosylase I -
  EL130_RS02360 (NCTC10832_00442) cinA 454362..455618 (+) 1257 WP_002283524.1 competence/damage-inducible protein A Machinery gene
  EL130_RS02365 (NCTC10832_00443) recA 455658..456809 (+) 1152 WP_002283523.1 recombinase RecA Machinery gene
  EL130_RS02370 (NCTC10832_00444) spx 456894..457292 (+) 399 WP_002262391.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 651 a.a.        Molecular weight: 73721.44 Da        Isoelectric Point: 6.4647

>NTDB_id=1001546 EL130_RS02345 WP_002283525.1 450840..452795(+) (hexB) [Streptococcus mutans strain NCTC10832]
MSKIIELPEVLANQIAAGEVIERPASVVKELVENAIDADSSQITIEIEESGLKKIQVTDNGQGIEQADVIMSLRRHATSK
IKKQSDLFRIRTLGFRGEALPSIASISRLTLKTATKGEIHGTLVIANGGKIEKEEAISTPIGTKVSVENLFFNTPARLKY
MKSLQAELAHIIDVINRLSLAHPEIAFTLIKDGRELTKTAGKGDLHQALAGIYGITTAKKMVEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMNLISS
AIADSLREQELIPDALENLAKTSTNKKQKFEQTQLPLKQSNLYYDKTQNDFFLKETTVSEASSEFTVVDKAVNITDNVSG
HSSVKYAQRQMRTCENKEHPSLAMTDKQQKRQLSRIVESLENEEKSTFPELEYFGQMHGTYLFAQGEGGLYIIDQHAAQE
RVKYEYYRDKIGEVDNSLQQLLVPYLFEFPANDFMTLQEKMGILNEVGIHLENYGENTFILREHPIWLQEKEIESAVYEM
CDMLLLTNEVSIKKYRAELAIMMSCKRSIKANHTLDDYSARNLLIQLSQCKNPYNCPHGRPVLVNFTKADMEKMFRRIQE
NHTSLRELGKY

Nucleotide


Download         Length: 1956 bp        

>NTDB_id=1001546 EL130_RS02345 WP_002283525.1 450840..452795(+) (hexB) [Streptococcus mutans strain NCTC10832]
ATGTCAAAAATTATTGAACTGCCAGAAGTTTTAGCTAATCAAATTGCTGCTGGAGAGGTTATTGAAAGACCAGCTAGTGT
CGTAAAAGAACTAGTTGAGAATGCTATTGACGCTGATAGCAGCCAAATTACAATAGAAATTGAAGAATCAGGACTGAAAA
AAATTCAAGTGACTGATAATGGTCAAGGAATAGAACAAGCGGATGTAATTATGAGCTTACGTCGTCATGCAACTAGTAAG
ATTAAAAAACAATCCGATCTTTTTAGAATTAGGACCTTAGGTTTTAGAGGTGAGGCCCTTCCATCAATTGCTTCTATTAG
CAGACTAACATTAAAAACAGCAACAAAAGGGGAAATACATGGCACTTTAGTAATCGCAAATGGAGGTAAAATTGAAAAAG
AAGAAGCCATTAGTACCCCTATTGGAACCAAAGTGAGTGTTGAAAATCTTTTCTTCAATACCCCTGCTCGCCTTAAATAT
ATGAAAAGTTTGCAGGCAGAACTTGCTCATATTATTGATGTCATTAACCGTCTTAGCTTGGCGCATCCCGAAATTGCTTT
CACGCTTATTAAAGATGGCCGTGAATTAACAAAGACGGCAGGTAAAGGCGATCTGCATCAAGCTTTAGCGGGTATTTATG
GGATAACCACTGCTAAAAAAATGGTCGAAATTTCAAATGCAGATCTTGATTTTGAAGTATCTGGTTATATTAGTTTGCCT
GAATTAACCCGAGCTAATCGCAATTATATTACCATTCTTATTAATGGGCGTTATATCAAAAATTTTTTGCTCAATCGCGC
TATTCTTGATGGTTATGGTTCAAAATTAATGGTGGGACGCTTTCCAATTGCTGTTATTGATATTCAGATTGACCCTTATT
TAGCAGATGTTAATGTTCATCCAACTAAGCAGGAAGTTCGCATTTCTAAAGAAAAAGAGTTAATGAATCTCATTAGTTCG
GCAATTGCAGATAGTTTAAGAGAACAAGAGTTAATTCCTGATGCTTTGGAAAATCTTGCTAAAACTAGCACAAACAAGAA
ACAAAAGTTTGAACAAACACAACTTCCTCTTAAACAATCAAATCTTTACTATGATAAGACTCAAAATGACTTCTTTCTCA
AAGAAACGACAGTTTCAGAAGCATCAAGCGAGTTTACAGTAGTTGATAAAGCTGTAAATATTACTGATAATGTATCAGGA
CATAGCAGTGTAAAATATGCTCAACGTCAAATGAGAACTTGTGAAAACAAAGAGCATCCAAGTCTTGCTATGACAGATAA
GCAACAAAAGCGACAACTTAGTAGAATTGTTGAAAGTCTAGAAAATGAAGAAAAGTCAACTTTTCCTGAGTTAGAATATT
TTGGTCAAATGCATGGAACTTACCTCTTTGCTCAAGGTGAAGGGGGGCTTTATATCATAGATCAACATGCTGCTCAAGAA
CGTGTTAAATATGAATATTATCGTGATAAAATTGGAGAAGTAGACAATAGTTTACAGCAGCTTTTAGTACCTTATCTTTT
TGAATTTCCTGCTAATGATTTTATGACCTTACAAGAAAAAATGGGCATTTTAAATGAGGTGGGAATTCACTTAGAAAACT
ATGGAGAGAATACTTTTATTTTGAGAGAACATCCTATTTGGTTACAGGAAAAAGAAATTGAATCAGCCGTTTATGAGATG
TGTGATATGTTGCTGTTGACAAATGAAGTCTCCATTAAGAAATATCGAGCGGAATTAGCTATTATGATGTCTTGCAAGCG
TTCTATCAAGGCTAATCATACTTTGGATGATTATTCTGCCAGAAATCTCTTAATTCAATTATCACAGTGCAAAAATCCTT
ACAATTGTCCTCATGGACGTCCTGTGCTTGTGAATTTCACAAAAGCTGATATGGAAAAGATGTTTCGTCGCATTCAGGAA
AACCATACTAGTTTGAGAGAATTAGGGAAATACTGA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-135)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

MutL C terminal dimerisation domain (MutL_C)

(453-595)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.909

100

0.707