Detailed information NTG1001460

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXR43_RS14325
• Genome accession: NZ_CP156038
• Coordinates: 2815213..2816100 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BSN77
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2810213..2821100

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR43_RS14295 (UXR43_14295)	-	2810232..2810324 (+)	93	WP_010956583.1	hypothetical protein	-
UXR43_RS14300 (UXR43_14300)	-	2810432..2810929 (-)	498	WP_001065268.1	glutathione peroxidase	-
UXR43_RS14305 (UXR43_14305)	-	2810939..2811199 (-)	261	WP_001789910.1	hypothetical protein	-
UXR43_RS14310 (UXR43_14310)	-	2811581..2811694 (-)	114	WP_001791776.1	hypothetical protein	-
UXR43_RS14315 (UXR43_14315)	-	2812353..2814353 (-)	2001	WP_000776751.1	ABC transporter permease	-
UXR43_RS14320 (UXR43_14320)	-	2814350..2815105 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXR43_RS14325 (UXR43_14325)	braS	2815213..2816100 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXR43_RS14330 (UXR43_14330)	braR	2816111..2816776 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXR43_RS14335 (UXR43_14335)	-	2816802..2817002 (-)	201	WP_000604728.1	hypothetical protein	-
UXR43_RS14340 (UXR43_14340)	-	2817200..2818624 (+)	1425	WP_000953744.1	alkaline phosphatase	-
UXR43_RS14345	-	2818684..2818785 (-)	102	WP_000731972.1	SE2200 family small protein	-
UXR43_RS14350 (UXR43_14350)	-	2818907..2819362 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXR43_RS14355 (UXR43_14355)	-	2819607..2820368 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1001460 UXR43_RS14325 WP_000143419.1 2815213..2816100(-) (braS) [Staphylococcus aureus strain BSN77]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1001460 UXR43_RS14325 WP_000143419.1 2815213..2816100(-) (braS) [Staphylococcus aureus strain BSN77]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997