Detailed information NTG1001122

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: EL186_RS22240
• Genome accession: NZ_LR134311
• Coordinates: 4605305..4606330 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain NCTC9113
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4600305..4611330

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL186_RS22230 (NCTC9113_04403)	rpmE	4602536..4602748 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
EL186_RS22235 (NCTC9113_04404)	priA	4602951..4605149 (+)	2199	WP_001315935.1	primosomal protein N'	Machinery gene
EL186_RS22240 (NCTC9113_04405)	cytR	4605305..4606330 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
EL186_RS22245 (NCTC9113_04406)	ftsN	4606422..4607381 (+)	960	WP_000068834.1	cell division protein FtsN	-
EL186_RS22250 (NCTC9113_04407)	hslV	4607474..4608004 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
EL186_RS22255 (NCTC9113_04408)	hslU	4608014..4609345 (+)	1332	WP_001293343.1	HslU--HslV peptidase ATPase subunit	-
EL186_RS22260 (NCTC9113_04409)	menA	4609412..4610338 (+)	927	WP_001307494.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
EL186_RS22265 (NCTC9113_04410)	rraA	4610431..4610916 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
EL186_RS22270 (NCTC9113_04411)	zapB	4611001..4611246 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=1001122 EL186_RS22240 WP_000644904.1 4605305..4606330(+) (cytR) [Escherichia coli strain NCTC9113]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=1001122 EL186_RS22240 WP_000644904.1 4605305..4606330(+) (cytR) [Escherichia coli strain NCTC9113]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACTGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAACCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGCTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTGCCTACCGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCACTGTGTCACTATCGCCTGCAAGGCTATGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628