Detailed information NTG1000178

Bioinformatically predicted

Overview

• Name: priA
• Type: Machinery gene
• Locus tag: EL092_RS03005
• Genome accession: NZ_LR134291
• Coordinates: 644743..647124 (+)
• Length: 793 a.a.
• NCBI ID: WP_012000090.1
• Uniprot ID: A8AVV2
• Organism: Streptococcus gordonii strain NCTC7868
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 639743..652124

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL092_RS02980 (NCTC7868_00590)	-	639754..641160 (+)	1407	WP_012000087.1	cell division site-positioning protein MapZ family protein	-
EL092_RS02985 (NCTC7868_00591)	luxS	641221..641703 (-)	483	WP_008808586.1	S-ribosylhomocysteine lyase	Regulator
EL092_RS02990 (NCTC7868_00592)	-	641935..643542 (+)	1608	WP_008808587.1	ribonuclease Y	-
EL092_RS02995 (NCTC7868_00593)	gmk	643657..644283 (+)	627	WP_012000088.1	guanylate kinase	-
EL092_RS03000 (NCTC7868_00594)	rpoZ	644308..644622 (+)	315	WP_041789567.1	DNA-directed RNA polymerase subunit omega	-
EL092_RS03005 (NCTC7868_00595)	priA	644743..647124 (+)	2382	WP_012000090.1	primosomal protein N'	Machinery gene
EL092_RS03010 (NCTC7868_00596)	fmt	647137..648072 (+)	936	WP_012000091.1	methionyl-tRNA formyltransferase	-
EL092_RS03015 (NCTC7868_00597)	rsmB	648062..649375 (+)	1314	WP_012000092.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
EL092_RS03020 (NCTC7868_00598)	-	649396..650136 (+)	741	WP_012000093.1	Stp1/IreP family PP2C-type Ser/Thr phosphatase	-
EL092_RS03025 (NCTC7868_00599)	stkP	650133..651986 (+)	1854	WP_012000094.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator

Sequence

Protein

• Length: 793 a.a.
• Molecular weight: 91163.28 Da
• Isoelectric Point: 7.6946

>NTDB_id=1000178 EL092_RS03005 WP_012000090.1 644743..647124(+) (priA) [Streptococcus gordonii strain NCTC7868]
MLVAKVIVDVPLMQTDKPFSYAVPQEFSQTLQVGMRVHVPFGKANRLIQGLVLAIEEEEGLGLKELVEVLDFSPVLNEEQ
LWLADELRKTVFSYKISILKAMLPNFLNSSYDKILYPTEEISLEERQEIFGEQTSLRFSDLDKERQATFMRLSQLGRIRM
EYQATDQKRIKTEKWYRVDHNSLVKMLISSRAKRKQDLKEYLLKQNEVQLLADLREKFSREVVQYFIDQNAIVVEEKEVS
RTASYFERERKDQKLQLNSEQEHAVAAITEKIGQDANPILLEGITGSGKTEVYLQVIEQVLQKGKTAIMLVPEISLTPQV
TDRFIARFGQQVAILHSGLSNGEKYDEWRKVERGEAQVVVGARSAVFAPLKNIGAIIIDEEHESSYKQDSNPRYHAREVA
ILRAQYNRAVLVLGSATPSLESRARAGKGRYQFLRLTKRANPLAKVPQVEVIDFRDYIGQNEAKNFTPPLLEAIQERLDR
REQVVLMLNRRGYSSFIMCRECGTVDTCPNCDISLTLHMDTKTMNCHYCGFVKDIPYACPNCSSRSMRYYGTGTQKAYDE
LKTAFPDARVLRMDVDTTRKKGSHEKILEAFGRGEADILLGTQMIAKGLDFPNVTLVGVLNADTALNLPDFRSSERTFQL
LTQVAGRAGRAEKEGQVLIQSYNPHHYAIEYAKKQDYEGFFNYEMNIRRQLGYPPYYFTVGLTLSHKDEEFLVKKSYQAL
DILRQGLSDQVKILGPTPKPIARTHNLFHYQILVKYRFEENLQGTLNKILEWTQERDNKDLRFSIDNEPQNFM

Nucleotide

• Length: 2382 bp

>NTDB_id=1000178 EL092_RS03005 WP_012000090.1 644743..647124(+) (priA) [Streptococcus gordonii strain NCTC7868]
ATGCTAGTTGCTAAAGTTATCGTAGATGTGCCCTTGATGCAGACTGACAAACCTTTCAGTTACGCAGTTCCTCAAGAGTT
TTCTCAAACCTTGCAAGTCGGGATGAGGGTTCACGTTCCTTTTGGAAAGGCCAATCGTTTGATTCAAGGGCTTGTTCTTG
CTATTGAAGAGGAAGAGGGATTGGGATTAAAAGAACTTGTTGAAGTTCTTGATTTTAGTCCGGTTTTAAACGAAGAGCAA
CTCTGGCTGGCAGATGAGCTGCGTAAAACAGTCTTCTCTTACAAAATTTCAATTTTAAAAGCCATGCTACCTAATTTTCT
TAACTCCTCTTATGACAAAATTCTCTATCCGACGGAAGAGATATCTTTAGAGGAGAGACAAGAGATTTTTGGTGAACAGA
CTAGTCTTCGTTTTTCTGATTTAGATAAGGAACGGCAAGCAACCTTTATGCGCTTGAGCCAATTAGGACGGATTCGTATG
GAGTATCAGGCAACAGATCAAAAACGAATCAAAACAGAGAAATGGTATAGGGTGGATCACAATTCTTTAGTAAAAATGCT
CATATCCAGTCGTGCTAAAAGAAAGCAGGATTTAAAAGAGTATTTACTGAAGCAAAACGAAGTACAGTTGCTGGCAGATT
TGCGGGAAAAATTTTCTAGAGAAGTGGTTCAATATTTTATAGACCAAAATGCAATTGTTGTTGAGGAAAAAGAAGTCAGT
AGAACGGCAAGCTATTTTGAAAGAGAGAGAAAGGACCAAAAATTACAGCTCAATAGTGAGCAAGAGCACGCTGTCGCTGC
GATAACTGAGAAGATTGGCCAAGATGCGAATCCGATTTTGCTAGAAGGAATCACAGGAAGTGGCAAGACAGAGGTTTATC
TTCAAGTAATTGAACAAGTCTTACAAAAAGGGAAAACTGCTATCATGCTGGTTCCTGAAATCTCTCTGACTCCACAAGTG
ACGGATCGTTTTATTGCCCGCTTTGGCCAACAGGTGGCAATCCTTCATTCTGGTTTGTCTAATGGTGAAAAATATGACGA
ATGGCGTAAGGTAGAAAGAGGGGAAGCCCAGGTCGTTGTTGGCGCGCGCTCAGCTGTCTTTGCCCCTCTCAAAAATATTG
GTGCAATTATTATTGATGAGGAGCACGAATCTTCATACAAGCAGGATTCTAATCCGCGTTACCATGCCCGAGAAGTTGCT
ATTCTCCGAGCTCAGTATAATCGGGCGGTTTTAGTTCTGGGGTCAGCAACGCCAAGTTTGGAAAGCAGAGCTAGAGCAGG
AAAGGGGCGGTATCAGTTTTTAAGGCTGACTAAGCGAGCTAATCCCCTAGCCAAGGTTCCGCAAGTTGAAGTCATTGATT
TTAGGGATTATATTGGTCAAAATGAAGCTAAGAACTTTACCCCTCCGCTTTTAGAGGCTATTCAAGAACGTTTGGATAGA
AGGGAGCAAGTTGTTCTCATGTTGAACCGCAGGGGCTATTCAAGTTTTATTATGTGCCGAGAATGCGGGACAGTGGACAC
TTGTCCAAACTGTGATATCTCTTTAACGCTTCATATGGATACCAAGACCATGAACTGTCATTACTGCGGTTTTGTCAAAG
ATATCCCCTATGCCTGCCCTAACTGTTCCAGCAGGAGTATGCGCTACTATGGAACGGGGACGCAGAAAGCCTATGATGAG
TTGAAAACAGCCTTTCCTGATGCGCGGGTCTTGAGAATGGATGTGGATACGACTCGAAAAAAAGGCAGTCATGAAAAGAT
TTTAGAAGCTTTTGGGCGAGGAGAAGCTGATATCTTGCTGGGAACCCAGATGATTGCTAAGGGCTTGGATTTTCCAAATG
TAACCTTGGTTGGGGTATTAAATGCGGACACAGCTCTGAATTTACCAGATTTTCGTTCTTCTGAGCGTACTTTCCAGCTT
TTGACTCAAGTAGCTGGTCGAGCAGGCCGCGCTGAAAAGGAAGGCCAAGTTTTGATTCAGTCCTACAACCCGCACCACTA
TGCTATAGAGTATGCTAAAAAGCAAGATTACGAAGGCTTTTTTAACTATGAAATGAACATTCGCAGGCAGCTTGGCTATC
CGCCTTATTATTTCACAGTTGGTTTGACCTTATCCCACAAAGATGAAGAATTTCTAGTTAAAAAATCCTACCAAGCTTTG
GATATTTTGAGGCAGGGGCTGTCTGACCAGGTTAAAATACTGGGTCCTACGCCCAAGCCAATTGCTCGAACACATAATCT
TTTTCATTATCAGATTCTGGTGAAATATCGTTTTGAAGAGAATTTGCAAGGAACTTTAAATAAGATTTTGGAATGGACTC
AGGAACGGGACAACAAGGACTTACGTTTTAGCATTGATAACGAACCACAAAACTTTATGTAA

Domains

Predicted by InterProScan.

• 3DNA-binding domain (3BD) (PriA_3primeBD) (5-104)

• Type III restriction enzyme, res subunit (ResIII) (254-419)

• PriA DNA helicase Cys-rich region (CRR) domain (Zn_ribbon_PriA) (508-532)

• Helicase conserved C-terminal domain (Helicase_C) (570-651)

• Primosomal protein N C-terminal domain (PriA_C) (695-789)

3D structure

• AlphaFold DB: A8AVV2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
priA	Bacillus subtilis subsp. subtilis str. 168	47.03	100	0.479