Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   EL070_RS07135 Genome accession   NZ_LR134284
Coordinates   1349987..1350775 (+) Length   262 a.a.
NCBI ID   WP_030127591.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8232     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1344987..1355775
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL070_RS07070 (NCTC8232_01426) - 1345001..1345207 (-) 207 WP_002988357.1 hypothetical protein -
  EL070_RS07075 (NCTC8232_01427) - 1345216..1345356 (-) 141 WP_002988354.1 hypothetical protein -
  EL070_RS07080 (NCTC8232_01428) - 1345353..1345586 (-) 234 WP_010922205.1 hypothetical protein -
  EL070_RS07085 (NCTC8232_01429) - 1345567..1345953 (-) 387 WP_002990076.1 DnaD domain-containing protein -
  EL070_RS10220 - 1346109..1346378 (-) 270 WP_011106700.1 replication protein -
  EL070_RS07095 (NCTC8232_01430) - 1346472..1346657 (-) 186 WP_032465394.1 hypothetical protein -
  EL070_RS07100 (NCTC8232_01431) - 1346659..1346796 (-) 138 WP_076639549.1 BOW99_gp33 family protein -
  EL070_RS07105 (NCTC8232_01432) - 1346883..1347065 (+) 183 WP_011889039.1 hypothetical protein -
  EL070_RS10380 (NCTC8232_01433) - 1347062..1347193 (-) 132 WP_002985401.1 hypothetical protein -
  EL070_RS07110 (NCTC8232_01434) - 1347206..1347967 (-) 762 WP_023610918.1 phage antirepressor KilAC domain-containing protein -
  EL070_RS07115 (NCTC8232_01435) - 1347978..1348217 (-) 240 WP_014411882.1 helix-turn-helix domain-containing protein -
  EL070_RS07120 (NCTC8232_01436) - 1348310..1348951 (+) 642 WP_001008979.1 hypothetical protein -
  EL070_RS07125 (NCTC8232_01437) - 1349050..1349208 (-) 159 WP_021340638.1 hypothetical protein -
  EL070_RS07130 (NCTC8232_01438) - 1349267..1349482 (+) 216 WP_014635530.1 hypothetical protein -
  EL070_RS10060 (NCTC8232_01439) - 1349468..1349617 (-) 150 WP_021340643.1 hypothetical protein -
  EL070_RS07135 (NCTC8232_01441) irvR 1349987..1350775 (+) 789 WP_030127591.1 S24 family peptidase Regulator
  EL070_RS07140 (NCTC8232_01442) - 1350785..1351090 (+) 306 WP_011106738.1 membrane protein -
  EL070_RS07145 (NCTC8232_01443) - 1351210..1352625 (+) 1416 WP_010922052.1 recombinase family protein -
  EL070_RS07150 (NCTC8232_01444) whiA 1352802..1353713 (-) 912 WP_011017562.1 DNA-binding protein WhiA -
  EL070_RS07155 (NCTC8232_01445) - 1353710..1354687 (-) 978 WP_011017561.1 YvcK family protein -
  EL070_RS07160 (NCTC8232_01446) rapZ 1354684..1355574 (-) 891 WP_002985434.1 RNase adapter RapZ -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 30036.18 Da        Isoelectric Point: 8.1141

>NTDB_id=1000055 EL070_RS07135 WP_030127591.1 1349987..1350775(+) (irvR) [Streptococcus pyogenes strain NCTC8232]
MARGRGKLTPQDEEYKKIISAKINSLLLENNLKQGHLADALEIPRSSFNEYVKGNSLPNPGNVQKIADYFGLMKSDIDPR
FAPRKKNHELKIPTSPLVKKITTTVVELNVPRKQKVLDFATEQLKEQKNKITSIEKKLYEYKVYEKLSAGTGYGYFGDGN
YDTVFYDEELDYDFASWVFGDSMEPTYLNGEVVLIKQTGFDYEGGIYAVEWDGQTYIKKVYREKDGLRLVSLNKKYNDKF
APFSEGPRIIGEIVGNFMPKEY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=1000055 EL070_RS07135 WP_030127591.1 1349987..1350775(+) (irvR) [Streptococcus pyogenes strain NCTC8232]
ATGGCAAGAGGACGAGGGAAATTAACACCTCAAGACGAGGAATACAAAAAGATAATTTCTGCTAAAATTAACAGTTTATT
GCTAGAAAACAATTTAAAACAAGGACATTTAGCTGATGCATTGGAAATTCCACGAAGTAGTTTTAATGAATATGTCAAAG
GAAATTCCTTACCTAATCCTGGTAACGTTCAAAAGATAGCTGATTATTTCGGGTTAATGAAGTCTGATATAGATCCTAGA
TTTGCACCTCGTAAGAAAAATCACGAACTCAAAATCCCTACTTCTCCACTTGTCAAAAAAATAACCACAACAGTCGTAGA
ATTAAATGTTCCTCGTAAGCAAAAAGTTTTAGACTTTGCAACAGAACAATTGAAAGAGCAAAAAAATAAAATTACTTCAA
TAGAGAAAAAACTATATGAATACAAAGTCTATGAGAAACTTTCCGCAGGTACAGGTTATGGATATTTTGGTGATGGGAAC
TATGATACTGTTTTTTACGACGAAGAATTAGATTACGATTTTGCCTCTTGGGTTTTTGGTGATTCTATGGAACCAACTTA
TCTGAATGGTGAGGTTGTGCTTATAAAACAAACTGGCTTTGATTATGAAGGTGGCATCTATGCCGTAGAGTGGGACGGAC
AAACCTATATTAAGAAAGTTTACAGAGAAAAGGATGGCTTGCGCCTTGTGTCTTTAAATAAAAAATACAATGACAAGTTT
GCTCCTTTTAGTGAAGGCCCTCGTATAATAGGGGAAATTGTCGGTAACTTTATGCCTAAAGAGTACTGA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(168-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

38.158

100

0.443

Multiple sequence alignment