Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1937339..1937521 Replicon chromosome
Accession NZ_CP026962
Organism Staphylococcus aureus strain FDAARGOS_6

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag RK64_RS14295 Protein ID WP_001801861.1
Coordinates 1937339..1937434 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1937462..1937521 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK64_RS09620 1932999..1933625 + 627 WP_000669046.1 hypothetical protein -
RK64_RS09625 1933666..1934010 + 345 WP_000627551.1 DUF3969 family protein -
RK64_RS09630 1934108..1934659 + 552 WP_000414205.1 hypothetical protein -
RK64_RS09635 1934877..1935518 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
RK64_RS09640 1935632..1935817 - 186 WP_000809857.1 hypothetical protein -
RK64_RS09645 1935819..1935995 - 177 WP_000375476.1 hypothetical protein -
RK64_RS09650 1936006..1936389 - 384 WP_000070812.1 hypothetical protein -
RK64_RS09660 1936993..1937136 - 144 WP_001549059.1 transposase -
RK64_RS14295 1937339..1937434 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1937462..1937521 - 60 - - Antitoxin
RK64_RS09670 1937557..1937658 + 102 WP_001791893.1 hypothetical protein -
RK64_RS09675 1937636..1937812 - 177 Protein_1822 transposase -
RK64_RS09680 1938006..1938383 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1930439..1970610 40171


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T96866 WP_001801861.1 NZ_CP026962:1937339-1937434 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T96866 NZ_CP026962:1937339-1937434 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT96866 NZ_CP026962:c1937521-1937462 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References