Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-SprF1/-
Location 82987..83325 Replicon chromosome
Accession NZ_CP026957
Organism Staphylococcus aureus strain FDAARGOS_43

Toxin (Protein)


Gene name txpA Uniprot ID Q2FWU9
Locus tag RL01_RS00500 Protein ID WP_011447039.1
Coordinates 82987..83163 (+) Length 59 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 83151..83325 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RL01_RS00480 80817..80969 + 153 WP_001000058.1 hypothetical protein -
RL01_RS00485 81015..81302 + 288 WP_001262624.1 hypothetical protein -
RL01_RS00490 81358..81732 + 375 WP_000340977.1 hypothetical protein -
RL01_RS00495 82105..82878 + 774 WP_000750412.1 staphylococcal enterotoxin type A -
RL01_RS00500 82987..83163 + 177 WP_011447039.1 putative holin-like toxin Toxin
- 83151..83325 - 175 - - Antitoxin
RL01_RS00510 83375..83629 + 255 WP_000611512.1 phage holin -
RL01_RS00515 83641..84396 + 756 WP_000861038.1 CHAP domain-containing protein -
RL01_RS00520 84587..85078 + 492 WP_000920039.1 staphylokinase -
RL01_RS00540 85729..86064 + 336 Protein_102 SH3 domain-containing protein -
RL01_RS00545 86576..86926 + 351 WP_000702263.1 complement inhibitor SCIN-A -
RL01_RS00550 86979..87239 - 261 WP_001791826.1 hypothetical protein -
RL01_RS00560 87550..87729 - 180 WP_000669791.1 hypothetical protein -
RL01_RS00565 88051..88301 - 251 Protein_106 sphingomyelin phosphodiesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / selq / sea / sak / scn 45585..86926 41341


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(30-58)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6849.45 Da        Isoelectric Point: 10.6777

>T96793 WP_011447039.1 NZ_CP026957:82987-83163 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK

Download         Length: 177 bp

>T96793 NZ_CP026957:82987-83163 [Staphylococcus aureus]
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA

Antitoxin


Download         Length: 175 bp

>AT96793 NZ_CP026957:c83325-83151 [Staphylococcus aureus]
ATTTGATATTTATATTATGGTGTGTTAATTTATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCC
GTTAAAAAGACGGTGGCTATTTTAGATTAAAGATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGAT
GGTTATTTTTTATTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 7NS1

Antitoxin

Download structure file

References