Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 208650..208832 Replicon chromosome
Accession NZ_CP026080
Organism Staphylococcus aureus strain FDAARGOS_12

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag RK70_RS14085 Protein ID WP_001801861.1
Coordinates 208737..208832 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 208650..208709 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK70_RS01250 207788..208165 + 378 WP_001037045.1 DUF1433 domain-containing protein -
RK70_RS01255 208359..208535 + 177 Protein_192 transposase -
RK70_RS01260 208513..208614 - 102 WP_001791893.1 hypothetical protein -
- 208650..208709 + 60 - - Antitoxin
RK70_RS14085 208737..208832 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
RK70_RS01270 209035..209178 + 144 WP_001549059.1 transposase -
RK70_RS01280 209782..210165 + 384 WP_000070812.1 hypothetical protein -
RK70_RS01285 210176..210352 + 177 WP_000375476.1 hypothetical protein -
RK70_RS01290 210354..210539 + 186 WP_000809857.1 hypothetical protein -
RK70_RS01295 210653..211294 + 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
RK70_RS01300 211512..212063 - 552 WP_000414205.1 hypothetical protein -
RK70_RS01305 212161..212505 - 345 WP_000627551.1 DUF3969 family protein -
RK70_RS01310 212546..213172 - 627 WP_000669046.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - hlgA / lukD 175561..215732 40171


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T93231 WP_001801861.1 NZ_CP026080:c208832-208737 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T93231 NZ_CP026080:c208832-208737 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT93231 NZ_CP026080:208650-208709 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References