80079

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1913314..1913496 Replicon chromosome
Accession NZ_CP022906
Organism Staphylococcus aureus strain 546

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CGP99_RS09795 Protein ID WP_001801861.1
Coordinates 1913314..1913409 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1913437..1913496 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP99_RS09745 1908974..1909600 + 627 WP_000669046.1 hypothetical protein -
CGP99_RS09750 1909641..1909985 + 345 WP_000627551.1 DUF3969 family protein -
CGP99_RS09755 1910083..1910634 + 552 WP_000414205.1 hypothetical protein -
CGP99_RS09760 1910852..1911493 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
CGP99_RS09765 1911607..1911792 - 186 WP_000809857.1 hypothetical protein -
CGP99_RS09770 1911794..1911970 - 177 WP_000375476.1 hypothetical protein -
CGP99_RS09775 1911981..1912364 - 384 WP_000070811.1 hypothetical protein -
CGP99_RS09785 1912968..1913111 - 144 WP_001549059.1 transposase -
CGP99_RS09795 1913314..1913409 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1913437..1913496 - 60 - - Antitoxin
CGP99_RS09800 1913532..1913633 + 102 WP_001791893.1 hypothetical protein -
CGP99_RS09805 1913611..1913787 - 177 Protein_1841 transposase -
CGP99_RS09810 1913981..1914358 - 378 WP_001037045.1 DUF1433 domain-containing protein -
CGP99_RS09815 1914879..1915706 - 828 Protein_1843 ATP-binding protein -
CGP99_RS09820 1915756..1916928 - 1173 WP_000195429.1 IS256-like element IS256 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1906414..1947802 41388
- flank IS/Tn - - 1915756..1916928 1172


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T80079 WP_001801861.1 NZ_CP022906:1913314-1913409 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T80079 NZ_CP022906:1913314-1913409 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT80079 NZ_CP022906:c1913496-1913437 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References