Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1913310..1913492 Replicon chromosome
Accession NZ_CP022902
Organism Staphylococcus aureus strain 165

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CGP98_RS09795 Protein ID WP_001801861.1
Coordinates 1913310..1913405 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1913433..1913492 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP98_RS09745 1908970..1909596 + 627 WP_000669046.1 hypothetical protein -
CGP98_RS09750 1909637..1909981 + 345 WP_000627551.1 DUF3969 family protein -
CGP98_RS09755 1910079..1910630 + 552 WP_000414205.1 hypothetical protein -
CGP98_RS09760 1910848..1911489 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
CGP98_RS09765 1911603..1911788 - 186 WP_000809857.1 hypothetical protein -
CGP98_RS09770 1911790..1911966 - 177 WP_000375476.1 hypothetical protein -
CGP98_RS09775 1911977..1912360 - 384 WP_000070811.1 hypothetical protein -
CGP98_RS09785 1912964..1913107 - 144 WP_001549059.1 transposase -
CGP98_RS09795 1913310..1913405 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1913433..1913492 - 60 - - Antitoxin
CGP98_RS09800 1913528..1913629 + 102 WP_001791893.1 hypothetical protein -
CGP98_RS09805 1913607..1913783 - 177 Protein_1840 transposase -
CGP98_RS09810 1913977..1914354 - 378 WP_001037045.1 DUF1433 domain-containing protein -
CGP98_RS09815 1914875..1915702 - 828 Protein_1842 ATP-binding protein -
CGP98_RS09820 1915752..1916924 - 1173 WP_000195429.1 IS256-like element IS256 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1906410..1947798 41388
- flank IS/Tn - - 1915752..1916924 1172


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T80010 WP_001801861.1 NZ_CP022902:1913310-1913405 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T80010 NZ_CP022902:1913310-1913405 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT80010 NZ_CP022902:c1913492-1913433 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References