Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1857758..1857940 Replicon chromosome
Accession NZ_CP020959
Organism Staphylococcus aureus strain H489

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag B9T45_RS09450 Protein ID WP_001801861.1
Coordinates 1857758..1857853 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1857881..1857940 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9T45_RS09400 1853418..1854044 + 627 WP_000669046.1 hypothetical protein -
B9T45_RS09405 1854085..1854429 + 345 WP_000627551.1 DUF3969 family protein -
B9T45_RS09410 1854527..1855078 + 552 WP_000414205.1 hypothetical protein -
B9T45_RS09415 1855296..1855937 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
B9T45_RS09420 1856051..1856236 - 186 WP_000809857.1 hypothetical protein -
B9T45_RS09425 1856238..1856414 - 177 WP_000375476.1 hypothetical protein -
B9T45_RS09430 1856425..1856808 - 384 WP_000070811.1 hypothetical protein -
B9T45_RS09440 1857412..1857555 - 144 WP_001549059.1 transposase -
B9T45_RS09450 1857758..1857853 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1857881..1857940 - 60 - - Antitoxin
B9T45_RS09455 1857976..1858077 + 102 WP_001791893.1 hypothetical protein -
B9T45_RS09460 1858055..1858231 - 177 Protein_1773 transposase -
B9T45_RS09465 1858425..1858802 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1850858..1894515 43657


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T75806 WP_001801861.1 NZ_CP020959:1857758-1857853 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T75806 NZ_CP020959:1857758-1857853 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT75806 NZ_CP020959:c1857940-1857881 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References