Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | sprA1-sprA1AS/- |
Location | 1857758..1857940 | Replicon | chromosome |
Accession | NZ_CP020959 | ||
Organism | Staphylococcus aureus strain H489 |
Toxin (Protein)
Gene name | sprA1 | Uniprot ID | - |
Locus tag | B9T45_RS09450 | Protein ID | WP_001801861.1 |
Coordinates | 1857758..1857853 (+) | Length | 32 a.a. |
Antitoxin (RNA)
Gene name | sprA1AS | ||
Locus tag | - | ||
Coordinates | 1857881..1857940 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
B9T45_RS09400 | 1853418..1854044 | + | 627 | WP_000669046.1 | hypothetical protein | - |
B9T45_RS09405 | 1854085..1854429 | + | 345 | WP_000627551.1 | DUF3969 family protein | - |
B9T45_RS09410 | 1854527..1855078 | + | 552 | WP_000414205.1 | hypothetical protein | - |
B9T45_RS09415 | 1855296..1855937 | - | 642 | WP_000494956.1 | ImmA/IrrE family metallo-endopeptidase | - |
B9T45_RS09420 | 1856051..1856236 | - | 186 | WP_000809857.1 | hypothetical protein | - |
B9T45_RS09425 | 1856238..1856414 | - | 177 | WP_000375476.1 | hypothetical protein | - |
B9T45_RS09430 | 1856425..1856808 | - | 384 | WP_000070811.1 | hypothetical protein | - |
B9T45_RS09440 | 1857412..1857555 | - | 144 | WP_001549059.1 | transposase | - |
B9T45_RS09450 | 1857758..1857853 | + | 96 | WP_001801861.1 | type I toxin-antitoxin system Fst family toxin PepA1 | Toxin |
- | 1857881..1857940 | - | 60 | - | - | Antitoxin |
B9T45_RS09455 | 1857976..1858077 | + | 102 | WP_001791893.1 | hypothetical protein | - |
B9T45_RS09460 | 1858055..1858231 | - | 177 | Protein_1773 | transposase | - |
B9T45_RS09465 | 1858425..1858802 | - | 378 | WP_001037045.1 | DUF1433 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | lukD / hlgA | 1850858..1894515 | 43657 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 32 a.a. Molecular weight: 3554.32 Da Isoelectric Point: 10.4449
>T75806 WP_001801861.1 NZ_CP020959:1857758-1857853 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK
Download Length: 96 bp
>T75806 NZ_CP020959:1857758-1857853 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG
Antitoxin
Download Length: 60 bp
>AT75806 NZ_CP020959:c1857940-1857881 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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