Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1852411..1852593 Replicon chromosome
Accession NZ_CP020957
Organism Staphylococcus aureus strain C3948

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag B9T42_RS09350 Protein ID WP_001801861.1
Coordinates 1852411..1852506 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1852534..1852593 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9T42_RS09300 1848071..1848697 + 627 WP_000669046.1 hypothetical protein -
B9T42_RS09305 1848738..1849082 + 345 WP_000627551.1 DUF3969 family protein -
B9T42_RS09310 1849180..1849731 + 552 WP_000414205.1 hypothetical protein -
B9T42_RS09315 1849949..1850590 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
B9T42_RS09320 1850704..1850889 - 186 WP_000809857.1 hypothetical protein -
B9T42_RS09325 1850891..1851067 - 177 WP_000375476.1 hypothetical protein -
B9T42_RS09330 1851078..1851461 - 384 WP_000070811.1 hypothetical protein -
B9T42_RS09340 1852065..1852208 - 144 WP_001549059.1 transposase -
B9T42_RS09350 1852411..1852506 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1852534..1852593 - 60 - - Antitoxin
B9T42_RS09355 1852629..1852730 + 102 WP_001791893.1 hypothetical protein -
B9T42_RS09360 1852708..1852884 - 177 Protein_1760 transposase -
B9T42_RS09365 1853078..1853455 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1845511..1885681 40170


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T75786 WP_001801861.1 NZ_CP020957:1852411-1852506 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T75786 NZ_CP020957:1852411-1852506 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT75786 NZ_CP020957:c1852593-1852534 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References