Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1891420..1891602 Replicon chromosome
Accession NZ_CP020956
Organism Staphylococcus aureus strain C8879

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag B9T41_RS09585 Protein ID WP_001801861.1
Coordinates 1891420..1891515 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1891543..1891602 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9T41_RS09535 1887080..1887706 + 627 WP_048519612.1 hypothetical protein -
B9T41_RS09540 1887747..1888091 + 345 WP_000627551.1 DUF3969 family protein -
B9T41_RS09545 1888189..1888740 + 552 WP_000414205.1 hypothetical protein -
B9T41_RS09550 1888958..1889599 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
B9T41_RS09555 1889713..1889898 - 186 WP_000809857.1 hypothetical protein -
B9T41_RS09560 1889900..1890076 - 177 WP_000375476.1 hypothetical protein -
B9T41_RS09565 1890087..1890470 - 384 WP_000070811.1 hypothetical protein -
B9T41_RS09575 1891074..1891217 - 144 WP_001549059.1 transposase -
B9T41_RS09585 1891420..1891515 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1891543..1891602 - 60 - - Antitoxin
B9T41_RS09590 1891638..1891739 + 102 WP_001791893.1 hypothetical protein -
B9T41_RS09595 1891717..1891893 - 177 Protein_1801 transposase -
B9T41_RS09600 1892087..1892464 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1884520..1924692 40172


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T75769 WP_001801861.1 NZ_CP020956:1891420-1891515 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T75769 NZ_CP020956:1891420-1891515 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT75769 NZ_CP020956:c1891602-1891543 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References