Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) CD-RCd/-
Location 2895469..2895686 Replicon chromosome
Accession NZ_CP020380
Organism Clostridioides difficile strain DSM 102978

Toxin (Protein)


Gene name CD2517.1 Uniprot ID -
Locus tag CDIF102978_RS14165 Protein ID WP_021375974.1
Coordinates 2895528..2895686 (-) Length 53 a.a.

Antitoxin (RNA)


Gene name CD630_n00500
Locus tag -
Coordinates 2895469..2895512 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDIF102978_RS14150 2891906..2893534 + 1629 WP_021376019.1 aspartate 4-decarboxylase -
CDIF102978_RS14155 2893655..2894650 + 996 WP_021376103.1 asparaginase -
CDIF102978_RS14160 2894812..2894982 - 171 WP_077708801.1 IS3 family transposase -
- 2895469..2895512 + 44 NuclAT_4 - Antitoxin
CDIF102978_RS14165 2895528..2895686 - 159 WP_021375974.1 hypothetical protein Toxin
CDIF102978_RS14170 2896108..2898528 - 2421 WP_021376018.1 leucine--tRNA ligase -
CDIF102978_RS14175 2898882..2899232 - 351 WP_003416416.1 ribosome silencing factor -
CDIF102978_RS14180 2899349..2899921 - 573 WP_003431048.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
CDIF102978_RS14185 2899922..2900611 - 690 WP_118090923.1 nicotinate-nucleotide adenylyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 53 a.a.        Molecular weight: 6026.23 Da        Isoelectric Point: 11.3102

>T74485 WP_021375974.1 NZ_CP020380:c2895686-2895528 [Clostridioides difficile]
MDNFLQGILASLSASLIVYITSKLFGKRKKPLKAATKSGWEFDFKIKFRRFK

Download         Length: 159 bp

>T74485 NZ_CP020380:c2895686-2895528 [Clostridioides difficile]
ATGGATAATTTTTTACAAGGTATACTAGCGAGTCTATCTGCTAGTTTAATAGTCTATATAACTAGCAAGTTATTTGGAAA
ACGTAAAAAACCACTCAAAGCTGCAACTAAGAGTGGTTGGGAGTTTGATTTTAAAATCAAATTCCGTAGATTTAAATAA

Antitoxin


Download         Length: 44 bp

>AT74485 NZ_CP020380:2895469-2895512 [Clostridioides difficile]
AAGAAGAACTACAATCTATTTAGACGTAGAGTGGAGTTCATAAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References