Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) CD-RCd/-
Location 2885839..2886056 Replicon chromosome
Accession NZ_CP020378
Organism Clostridioides difficile strain DSM 102859

Toxin (Protein)


Gene name CD2517.1 Uniprot ID -
Locus tag CDIF102859_RS14010 Protein ID WP_021375974.1
Coordinates 2885898..2886056 (-) Length 53 a.a.

Antitoxin (RNA)


Gene name CD630_n00500
Locus tag -
Coordinates 2885839..2885882 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDIF102859_RS13995 2882276..2883904 + 1629 WP_021376019.1 aspartate 4-decarboxylase -
CDIF102859_RS14000 2884025..2885020 + 996 WP_021376103.1 asparaginase -
CDIF102859_RS14005 2885182..2885352 - 171 WP_077708801.1 IS3 family transposase -
- 2885839..2885882 + 44 NuclAT_2 - Antitoxin
CDIF102859_RS14010 2885898..2886056 - 159 WP_021375974.1 hypothetical protein Toxin
CDIF102859_RS14015 2886478..2888898 - 2421 WP_021376018.1 leucine--tRNA ligase -
CDIF102859_RS14020 2889252..2889602 - 351 WP_003416416.1 ribosome silencing factor -
CDIF102859_RS14025 2889719..2890291 - 573 WP_003431048.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
CDIF102859_RS14030 2890292..2890981 - 690 WP_003416411.1 nicotinate-nucleotide adenylyltransferase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 53 a.a.        Molecular weight: 6026.23 Da        Isoelectric Point: 11.3102

>T74467 WP_021375974.1 NZ_CP020378:c2886056-2885898 [Clostridioides difficile]
MDNFLQGILASLSASLIVYITSKLFGKRKKPLKAATKSGWEFDFKIKFRRFK

Download         Length: 159 bp

>T74467 NZ_CP020378:c2886056-2885898 [Clostridioides difficile]
ATGGATAATTTTTTACAAGGTATACTAGCGAGTCTATCTGCTAGTTTAATAGTCTATATAACTAGCAAGTTATTTGGAAA
ACGTAAAAAACCACTCAAAGCTGCAACTAAGAGTGGTTGGGAGTTTGATTTTAAAATCAAATTCCGTAGATTTAAATAA

Antitoxin


Download         Length: 44 bp

>AT74467 NZ_CP020378:2885839-2885882 [Clostridioides difficile]
AAGAAGAACTACAATCTATTTAGACGTAGAGTGGAGTTCATAAT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References