Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3067566..3067800 | Replicon | chromosome |
| Accession | NZ_CP020342 | ||
| Organism | Shigella flexneri 1a strain 0439 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3067696..3067799 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3067566..3067800 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BS647_RS16375 | 3064121..3064783 | - | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
| BS647_RS16380 | 3064807..3065463 | - | 657 | Protein_2950 | carbon-nitrogen hydrolase family protein | - |
| BS647_RS16385 | 3065565..3065795 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| BS647_RS16390 | 3065934..3066308 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| BS647_RS16395 | 3066312..3067184 | + | 873 | Protein_2953 | copper homeostasis membrane protein CopD | - |
| BS647_RS16400 | 3067197..3067538 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 3067566..3067800 | - | 235 | - | - | Antitoxin |
| - | 3067696..3067799 | + | 104 | - | - | Toxin |
| BS647_RS28435 | 3067931..3069008 | - | 1078 | Protein_2955 | phage integrase Arm DNA-binding domain-containing protein | - |
| BS647_RS16415 | 3068974..3069255 | - | 282 | WP_005127484.1 | excisionase | - |
| BS647_RS16425 | 3070592..3071059 | + | 468 | Protein_2958 | DNA-binding transcriptional regulator PgrR | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| inside | Prophage | - | - | 3062064..3077205 | 15141 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T74315 NZ_CP020342:3067696-3067799 [Shigella flexneri 1a]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT74315 NZ_CP020342:c3067800-3067566 [Shigella flexneri 1a]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
