Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3067566..3067800 Replicon chromosome
Accession NZ_CP020342
Organism Shigella flexneri 1a strain 0439

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3067696..3067799 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3067566..3067800 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BS647_RS16375 3064121..3064783 - 663 WP_000944268.1 exodeoxyribonuclease X -
BS647_RS16380 3064807..3065463 - 657 Protein_2950 carbon-nitrogen hydrolase family protein -
BS647_RS16385 3065565..3065795 - 231 WP_000916763.1 DNA polymerase III subunit theta -
BS647_RS16390 3065934..3066308 + 375 WP_000168747.1 CopC domain-containing protein YobA -
BS647_RS16395 3066312..3067184 + 873 Protein_2953 copper homeostasis membrane protein CopD -
BS647_RS16400 3067197..3067538 + 342 WP_000976476.1 YebY family protein -
- 3067566..3067800 - 235 - - Antitoxin
- 3067696..3067799 + 104 - - Toxin
BS647_RS28435 3067931..3069008 - 1078 Protein_2955 phage integrase Arm DNA-binding domain-containing protein -
BS647_RS16415 3068974..3069255 - 282 WP_005127484.1 excisionase -
BS647_RS16425 3070592..3071059 + 468 Protein_2958 DNA-binding transcriptional regulator PgrR -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 3062064..3077205 15141


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences

Toxin        


Download         Length: 104 bp

>T74315 NZ_CP020342:3067696-3067799 [Shigella flexneri 1a]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT74315 NZ_CP020342:c3067800-3067566 [Shigella flexneri 1a]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures

Antitoxin

Download structure file

Antitoxin

Download structure file

References