74267

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2047661..2047895 Replicon chromosome
Accession NZ_CP020336
Organism Shigella flexneri 4c strain 1602

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2047662..2047765 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2047661..2047895 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BS654_RS11325 2043107..2043574 - 468 Protein_2080 DNA-binding transcriptional regulator PgrR -
BS654_RS11330 2043638..2043948 + 311 Protein_2081 transposase -
BS654_RS11335 2043991..2045186 - 1196 Protein_2082 IS3 family transposase -
BS654_RS11340 2045241..2046089 + 849 Protein_2083 IS3-like element IS600 family transposase -
BS654_RS11345 2046206..2046487 + 282 WP_005127484.1 excisionase -
BS654_RS28980 2046453..2047530 + 1078 Protein_2085 phage integrase Arm DNA-binding domain-containing protein -
- 2047661..2047895 + 235 - - Antitoxin
- 2047662..2047765 - 104 - - Toxin
BS654_RS11360 2047923..2048264 - 342 WP_000976476.1 YebY family protein -
BS654_RS11365 2048277..2049149 - 873 Protein_2087 copper homeostasis membrane protein CopD -
BS654_RS11370 2049153..2049527 - 375 WP_000168747.1 CopC domain-containing protein YobA -
BS654_RS11375 2049666..2049896 + 231 WP_000916763.1 DNA polymerase III subunit theta -
BS654_RS11380 2049998..2050654 + 657 Protein_2090 carbon-nitrogen hydrolase family protein -
BS654_RS11385 2050678..2051340 + 663 WP_000944268.1 exodeoxyribonuclease X -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2034691..2053397 18706


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences

Toxin        


Download         Length: 104 bp

>T74267 NZ_CP020336:c2047765-2047662 [Shigella flexneri 4c]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT74267 NZ_CP020336:2047661-2047895 [Shigella flexneri 4c]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures

Antitoxin

Download structure file

Antitoxin

Download structure file

References