Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) CD-RCd/-
Location 1502978..1503174 Replicon chromosome
Accession NZ_CP019860
Organism Clostridioides difficile strain DSM 29632

Toxin (Protein)


Gene name CD1418.2 Uniprot ID Q18BT8
Locus tag CDIF29632_RS07195 Protein ID WP_009902496.1
Coordinates 1502978..1503130 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name CD630_n00500
Locus tag -
Coordinates 1503074..1503174 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDIF29632_RS07165 1498518..1499111 - 594 WP_003438546.1 DUF308 domain-containing protein -
CDIF29632_RS07170 1499218..1499646 + 429 WP_003429356.1 DMT family transporter -
CDIF29632_RS07175 1499713..1500381 + 669 WP_032507408.1 diphthine--ammonia ligase -
CDIF29632_RS07180 1500499..1501854 - 1356 WP_003438549.1 MATE family efflux transporter -
CDIF29632_RS07195 1502978..1503130 + 153 WP_009902496.1 hypothetical protein Toxin
- 1503074..1503174 - 101 NuclAT_6 - Antitoxin
CDIF29632_RS07200 1504690..1506423 - 1734 WP_070538191.1 diguanylate cyclase -
CDIF29632_RS07205 1506663..1507508 - 846 WP_009889222.1 GGDEF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5742.81 Da        Isoelectric Point: 10.9178

>T73369 WP_009902496.1 NZ_CP019860:1502978-1503130 [Clostridioides difficile]
MDNFLQGVLASLVASLIVYLNSKLFKKVKSHSGRSDFSFELKIKFKKNKH

Download         Length: 153 bp

>T73369 NZ_CP019860:1502978-1503130 [Clostridioides difficile]
ATGGATAATTTTTTACAAGGTGTACTAGCAAGTTTAGTTGCCAGTTTAATAGTTTACTTAAATAGTAAATTATTTAAAAA
AGTAAAAAGCCACTCTGGCAGGAGCGACTTTAGTTTTGAACTAAAAATCAAGTTCAAAAAGAATAAACATTAG

Antitoxin


Download         Length: 101 bp

>AT73369 NZ_CP019860:c1503174-1503074 [Clostridioides difficile]
AAGAAGAACTACAATCTATTTAGACATAGAGTGAAGTTCAAATACTAATGTTTATTCTTTTTGAACTTGATTTTTAGTTC
AAAACTAAAGTCGCTCCTGCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A069ACY9

Antitoxin

Download structure file

References