Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) CD-RCd/-
Location 1291943..1292148 Replicon chromosome
Accession NZ_CP019860
Organism Clostridioides difficile strain DSM 29632

Toxin (Protein)


Gene name CD1233.1 Uniprot ID A0A069A9H6
Locus tag CDIF29632_RS06160 Protein ID WP_009896140.1
Coordinates 1291943..1292095 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name SQ808
Locus tag -
Coordinates 1292075..1292148 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDIF29632_RS06140 1287405..1287689 - 285 WP_003419254.1 sigma-70 family RNA polymerase sigma factor -
CDIF29632_RS06145 1287712..1289229 - 1518 WP_003438169.1 recombinase family protein -
CDIF29632_RS06150 1289354..1290175 - 822 WP_070538406.1 tetratricopeptide repeat protein -
CDIF29632_RS06155 1290366..1291793 + 1428 WP_074431859.1 cell wall-binding protein Cwp26 -
CDIF29632_RS06160 1291943..1292095 + 153 WP_009896140.1 hypothetical protein Toxin
- 1292075..1292148 - 74 NuclAT_7 - Antitoxin
CDIF29632_RS06170 1294946..1295101 + 156 WP_003438173.1 hypothetical protein -
CDIF29632_RS06180 1295347..1295598 + 252 WP_003419270.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5811.96 Da        Isoelectric Point: 11.1039

>T73367 WP_009896140.1 NZ_CP019860:1291943-1292095 [Clostridioides difficile]
MDNFLFNVLASLTASVVVYLISKLFKKAKSHSRTKSDLRVEFKFIFKSKK

Download         Length: 153 bp

>T73367 NZ_CP019860:1291943-1292095 [Clostridioides difficile]
ATGGATAACTTTTTGTTTAATGTTTTAGCTAGTTTAACAGCTAGTGTGGTAGTTTACTTAATCAGTAAACTATTCAAAAA
AGCAAAAAGCCACTCTCGCACAAAGAGTGACTTACGAGTTGAATTTAAATTTATATTTAAATCCAAAAAATAA

Antitoxin


Download         Length: 74 bp

>AT73367 NZ_CP019860:c1292148-1292075 [Clostridioides difficile]
AAGAAGAACTACAATCTATTTTGCGTTAGAGTGGAGTTCATCATAAACAGAGTTTATTTTTTGGATTTAAATAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A069A9H6

Antitoxin

Download structure file

References